ID A0A0S1XY41_9BORD Unreviewed; 524 AA.
AC A0A0S1XY41;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=argininosuccinate lyase {ECO:0000256|ARBA:ARBA00012338};
DE EC=4.3.2.1 {ECO:0000256|ARBA:ARBA00012338};
GN ORFNames=ASB57_07035 {ECO:0000313|EMBL:ALM82740.1};
OS Bordetella sp. N.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=1746199 {ECO:0000313|EMBL:ALM82740.1, ECO:0000313|Proteomes:UP000064621};
RN [1] {ECO:0000313|EMBL:ALM82740.1, ECO:0000313|Proteomes:UP000064621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N {ECO:0000313|EMBL:ALM82740.1,
RC ECO:0000313|Proteomes:UP000064621};
RA Hou L.;
RT "Draft genome of Bordetella sp. N.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2-(N(omega)-L-arginino)succinate = fumarate + L-arginine;
CC Xref=Rhea:RHEA:24020, ChEBI:CHEBI:29806, ChEBI:CHEBI:32682,
CC ChEBI:CHEBI:57472; EC=4.3.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000985};
CC -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine
CC from L-ornithine and carbamoyl phosphate: step 3/3.
CC {ECO:0000256|ARBA:ARBA00004941}.
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DR EMBL; CP013111; ALM82740.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S1XY41; -.
DR STRING; 1746199.ASB57_07035; -.
DR UniPathway; UPA00068; UER00114.
DR Proteomes; UP000064621; Chromosome.
DR GO; GO:0004056; F:argininosuccinate lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR CDD; cd01359; Argininosuccinate_lyase; 1.
DR Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR InterPro; IPR029419; Arg_succ_lyase_C.
DR InterPro; IPR009049; Argininosuccinate_lyase.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR000362; Fumarate_lyase_fam.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR PANTHER; PTHR43814; ARGININOSUCCINATE LYASE; 1.
DR PANTHER; PTHR43814:SF1; ARGININOSUCCINATE LYASE; 1.
DR Pfam; PF14698; ASL_C2; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00145; ARGSUCLYASE.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022571};
KW Arginine biosynthesis {ECO:0000256|ARBA:ARBA00022571};
KW Lyase {ECO:0000313|EMBL:ALM82740.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000064621}.
FT DOMAIN 116..309
FT /note="Fumarate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00206"
FT DOMAIN 384..460
FT /note="Argininosuccinate lyase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14698"
FT REGION 15..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 524 AA; 57174 MW; 76F3D51E3489C569 CRC64;
MALACAPALT AAQIKPVEPA AGNAEKPSAK PAEKPATKAP AKPVRDEFFW LGEINKATAV
INTDEGLLDK SMAPRLAAAV QKVIDDGNQP GGKRPSTVIT FEPLLIKAGG LDVTLLHAGR
SSQDMHATYR SAILRDKLLE LADQLHATSK TLVDLAAKHV DTIVPNYTNG VAAQPNSYGH
YLLGFAAALE RDAQRIQETY ARVDRSPMGT TVLNGTSWPL NRKRMADYLG YAKLVDNAYD
AAQISSMDEP VEVSSIVTAI GLHTGNFIED IMTQYAQSRP WILLQEGGGN TYVSSAMPQK
RNPGLLNSTR SDASTALTLA MGPIIQTHNI TPGMPDPKEV DQNSAMVDAA IKALKKWDRV
LKALVINPDR ALEELNSDWT ASQELADLLM RKYKLPFREG HHFASEVVEY ARQHDIKPLA
FPYADAKRIY ADVVKGSKYP QELPMSEAEF RASLDPVAIV KARATSGGPQ PAEMERMLKE
ARDNLAQQDT WIKSHRSHID DALARLNKDF DTLVAQGDKA TPAK
//
