ID A0A0S2DMI4_LYSEN Unreviewed; 300 AA.
AC A0A0S2DMI4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=6-phosphogluconate dehydrogenase (Decarboxylating) {ECO:0000313|EMBL:ALN59716.1};
DE EC=1.1.1.44 {ECO:0000313|EMBL:ALN59716.1};
DE SubName: Full=Decarboxylating 6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:QCW27814.1};
GN Name=gnd {ECO:0000313|EMBL:ALN59716.1};
GN ORFNames=BV903_004205 {ECO:0000313|EMBL:UZW61513.1}, FE772_21375
GN {ECO:0000313|EMBL:QCW27814.1}, GLE_4375 {ECO:0000313|EMBL:ALN59716.1};
OS Lysobacter enzymogenes.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=69 {ECO:0000313|EMBL:ALN59716.1, ECO:0000313|Proteomes:UP000061569};
RN [1] {ECO:0000313|EMBL:ALN59716.1, ECO:0000313|Proteomes:UP000061569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C3 {ECO:0000313|EMBL:ALN59716.1,
RC ECO:0000313|Proteomes:UP000061569};
RA Kobayashi D.Y.;
RT "Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter
RT antibioticus ATCC 29479.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:UZW61513.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B25 {ECO:0000313|EMBL:UZW61513.1};
RX PubMed=28473380; DOI=10.1128/genomea.00271-17;
RA Hernandez I., Fernandez C.;
RT "Draft Genome Sequence and Assembly of a Lysobacter enzymogenes Strain with
RT Biological Control Activity against Root Knot Nematodes.";
RL Genome Announc. 5:e00271-e00217(2017).
RN [3] {ECO:0000313|EMBL:QCW27814.1, ECO:0000313|Proteomes:UP000308311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YC36 {ECO:0000313|EMBL:QCW27814.1,
RC ECO:0000313|Proteomes:UP000308311};
RA Feng T.;
RT "Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically
RT Regulate the Twitching Motility of Lysobacter enzymogenes.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:UZW61513.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B25 {ECO:0000313|EMBL:UZW61513.1};
RA Fernandez G., Fernandez C., Hernandez I.;
RT "Improved assembly of Lysobacter enzymogenes B25.";
RL Submitted (OCT-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway.
CC {ECO:0000256|ARBA:ARBA00004959}.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
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DR EMBL; CP013140; ALN59716.1; -; Genomic_DNA.
DR EMBL; CP040656; QCW27814.1; -; Genomic_DNA.
DR EMBL; CP110813; UZW61513.1; -; Genomic_DNA.
DR RefSeq; WP_057949001.1; NZ_CP110813.1.
DR STRING; 69.GLE_4375; -.
DR KEGG; lez:GLE_4375; -.
DR PATRIC; fig|69.6.peg.4314; -.
DR OrthoDB; 9804542at2; -.
DR UniPathway; UPA00115; -.
DR Proteomes; UP000061569; Chromosome.
DR Proteomes; UP000190203; Chromosome.
DR Proteomes; UP000308311; Chromosome.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR004849; 6DGDH_YqeC.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR NCBIfam; TIGR00872; gnd_rel; 1.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF67; 6-PHOSPHOGLUCONATE DEHYDROGENASE YQEC-RELATED; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ALN59716.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000061569}.
FT DOMAIN 168..296
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
SQ SEQUENCE 300 AA; 31837 MW; C21D2DC8D8C720E6 CRC64;
MELGMVGLGR MGANMAERLV RGGHTVVGFD PGAAAREQAA ARGIGAAASL AELVAALPAP
RTLWLMVPAG AVDATLAELR PLLAAGDTVV DGGNSNYKDT VRRAGELLAH DLHYVDSGTS
GGVWGLQEGY SLMIGGEEAA VERLRPIFET LAPAAERGWG RVGPSGAGHF TKMIHNGIEY
GMMQAYAEGF AILGRKAEFG LDLHQIAQIW RHGSVVRSWL LDLSADALGK NPDLQGIAPY
VEDSGEGRWT VAEAIDLDVS APVITASLME RLRSREKDSF ADKLLAAMRN EFGGHAIRKE
//
