ID A0A0S2K4B8_9GAMM Unreviewed; 252 AA.
AC A0A0S2K4B8;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Pyruvate dehydrogenase complex repressor {ECO:0000256|ARBA:ARBA00039592};
GN ORFNames=C1E24_14620 {ECO:0000313|EMBL:TLX46256.1}, PP2015_2476
GN {ECO:0000313|EMBL:ALO42968.1};
OS Pseudoalteromonas phenolica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=161398 {ECO:0000313|EMBL:ALO42968.1, ECO:0000313|Proteomes:UP000061457};
RN [1] {ECO:0000313|EMBL:ALO42968.1, ECO:0000313|Proteomes:UP000061457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 12086 {ECO:0000313|EMBL:ALO42968.1,
RC ECO:0000313|Proteomes:UP000061457};
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TLX46256.1, ECO:0000313|Proteomes:UP000309186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S3663 {ECO:0000313|EMBL:TLX46256.1,
RC ECO:0000313|Proteomes:UP000309186};
RA Paulsen S., Gram L., Machado H.;
RT "Co-occurrence of chitin degradation, pigmentation and bioactivity in
RT marine Pseudoalteromonas.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcriptional repressor for the pyruvate dehydrogenase
CC complex genes aceEF and lpd. {ECO:0000256|ARBA:ARBA00037357}.
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DR EMBL; CP013187; ALO42968.1; -; Genomic_DNA.
DR EMBL; PPSW01000024; TLX46256.1; -; Genomic_DNA.
DR RefSeq; WP_058030666.1; NZ_PPSW01000024.1.
DR AlphaFoldDB; A0A0S2K4B8; -.
DR STRING; 161398.PP2015_2476; -.
DR KEGG; pphe:PP2015_2476; -.
DR PATRIC; fig|161398.10.peg.2530; -.
DR OrthoDB; 5450856at2; -.
DR Proteomes; UP000061457; Chromosome I.
DR Proteomes; UP000309186; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF34; PYRUVATE DEHYDROGENASE COMPLEX REPRESSOR; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyruvate {ECO:0000313|EMBL:TLX46256.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000061457};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..76
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 252 AA; 28320 MW; 99BDCB05820A28BD CRC64;
MSLKIKAAKL SDVILEQLEN MILEGSLMPG EKLPPERELA KQFEVSRPSL REAIQKLEAK
GLVTRRQGGG TYVKNQLEQG LTDPLFDLIS KHPESQFDLL EFRHALEGIA AYYAALRGTD
TDFEKVQQSF DNIADVHGDL EQKAQAINAF HFAVAEASHN VVLLHLVKGM QSLLEQNVLQ
NLQVLVQKNN VSEQLAEHRK LLMDAVIEGN PEQARLASNA HLAFIEEALL EADKERSRIA
RSLRRTSNNR VR
//
