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Database: UniProt
Entry: A0A0S2K8N0_9GAMM
LinkDB: A0A0S2K8N0_9GAMM
Original site: A0A0S2K8N0_9GAMM 
ID   A0A0S2K8N0_9GAMM        Unreviewed;       498 AA.
AC   A0A0S2K8N0;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   23-MAY-2018, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=PS2015_1 {ECO:0000313|EMBL:ALO44699.1};
OS   Pseudohongiella spirulinae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudohongiella.
OX   NCBI_TaxID=1249552 {ECO:0000313|EMBL:ALO44699.1, ECO:0000313|Proteomes:UP000065641};
RN   [1] {ECO:0000313|EMBL:ALO44699.1, ECO:0000313|Proteomes:UP000065641}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KCTC 32221 {ECO:0000313|EMBL:ALO44699.1,
RC   ECO:0000313|Proteomes:UP000065641};
RA   Zhang Y., Guo Z.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00747961}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP013189; ALO44699.1; -; Genomic_DNA.
DR   RefSeq; WP_058023057.1; NZ_CP013189.1.
DR   EnsemblBacteria; ALO44699; ALO44699; PS2015_1.
DR   KEGG; pspi:PS2015_1; -.
DR   PATRIC; fig|1249552.3.peg.1; -.
DR   KO; K02313; -.
DR   Proteomes; UP000065641; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000065641};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747973};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00748008};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000065641}.
FT   DOMAIN      195    404       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      406    475       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     203    210       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   498 AA;  56040 MW;  7FF5BA8AA5B77583 CRC64;
     MLQTTWQQCV EHLRDELPSQ QFNTWIRPLQ AEFYSHQLIL FAPNRFVQDW VRDKFHSRII
     EFVKTQTGND QLTVDIEVGG GNSIQSAALS RSPETARKME IPDAAEKNSE ELGRLGGEVL
     KGFSKDRAKE SSLSKSTHDR RGSATAKKMD LIIEGKLRHK GSLNSENTFD NFIEGKSNQL
     ARAAAMQVAE NPGGAYNPLF IYGGVGLGKT HLMHAIGNHM LAHKPDARVV YLHSETFVAT
     MVTALQLNAI NEFKRYYRSV DALLIDDIQF FAGKERSQEE FFHTFNALLE GGQQIILTSD
     RYHKEINGLE ERLKSRFGWG LSVAVEPPEL ETRAAILINK AAQSNVDLPG DAAMFIAQRL
     RSHVRELEGA LKKVIIHANF VGRPIDLDLV REALRDLFAL HDKLVSVDNI QRTVAEYYKI
     KMSDMLSKRR NRSVARPRQI AMSLAKELTN HSLPEIGDAF GGRDHTTVLH ACKQVKNLRG
     SSQDLAEDYN NLLRALAT
//
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