ID A0A0S2TD66_9GAMM Unreviewed; 811 AA.
AC A0A0S2TD66;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=endopeptidase La {ECO:0000256|PROSITE-ProRule:PRU01122};
DE EC=3.4.21.53 {ECO:0000256|PROSITE-ProRule:PRU01122};
GN ORFNames=Tel_07890 {ECO:0000313|EMBL:ALP53082.1};
OS Candidatus Tenderia electrophaga.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Tenderia.
OX NCBI_TaxID=1748243 {ECO:0000313|EMBL:ALP53082.1, ECO:0000313|Proteomes:UP000055136};
RN [1] {ECO:0000313|EMBL:ALP53082.1, ECO:0000313|Proteomes:UP000055136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRL1 {ECO:0000313|EMBL:ALP53082.1};
RA Eddie B.J., Malanoski A.P., Wang Z., Hall R.J., Oh S.D., Heiner C., Lin B.,
RA Strycharz-Glaven S.M.;
RT "Description of Candidatus Tenderia electrophaga gen. nov, sp. nov., an
RT Uncultivated Electroautotroph from a Biocathode Enrichment.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of proteins in presence of ATP.; EC=3.4.21.53;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU01122};
CC -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01122}.
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DR EMBL; CP013099; ALP53082.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S2TD66; -.
DR STRING; 1748243.Tel_07890; -.
DR KEGG; tee:Tel_07890; -.
DR Proteomes; UP000055136; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041699; AAA_32.
DR InterPro; IPR046844; Lon-like_helical.
DR InterPro; IPR008269; Lon_proteolytic.
DR InterPro; IPR027065; Lon_Prtase.
DR InterPro; IPR046843; LonB_AAA-LID.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10046:SF46; ARCHAEAL LON PROTEASE; 1.
DR PANTHER; PTHR10046; ATP DEPENDENT LON PROTEASE FAMILY MEMBER; 1.
DR Pfam; PF13654; AAA_32; 1.
DR Pfam; PF05362; Lon_C; 1.
DR Pfam; PF20436; LonB_AAA-LID; 1.
DR Pfam; PF20437; LonC_helical; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS51786; LON_PROTEOLYTIC; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01122};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01122}; Reference proteome {ECO:0000313|Proteomes:UP000055136};
KW Serine protease {ECO:0000256|PROSITE-ProRule:PRU01122}.
FT DOMAIN 564..759
FT /note="Lon proteolytic"
FT /evidence="ECO:0000259|PROSITE:PS51786"
FT COILED 135..166
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 654
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
FT ACT_SITE 697
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
SQ SEQUENCE 811 AA; 89742 MW; 8991828CBABB5628 CRC64;
MSNIKPLQAQ ALFQACDPSQ FDFDSTAELD DLSEVIGQAR ALEAIHFGMG IKKKGYNIFA
LGPAGTGKHN VVTHLLKQQA SSEAAPCDWC YVNNFDAPHK PIALGLPPGT GRKLHDDMKQ
LVEELRAAIP ALFEGDEYRA SIHELEEELK NQQERAIDEV RQAAQQKSIA LIRTPNGFAF
APARDDEVID PKEFKKLPDD VKHKFEAEIA ELQEALEHIL RMAPQWRREA RERIKQLNAE
LAMSAVGHLI DELREHYQDQ DEVLKYLDSV QEDVIANVDD FRRGEEEDAQ VVIGPNHSGG
SFRRYQVNVL VDHSDSQGAP VVYEDNPTYQ NLIGRVEHMA MMGALITDFT LIKPGALHRA
NNGYLVLEVY KLFQHPFSWE AIKRTLRSGE ICIGSLEQML SLVSTVSLEP EPVPLNVKVV
LVGDRMLYYL LYQLDPEFQE LFKVAADFDD QMERSTESQQ LYAHLIATLA KKDKLRPFDR
SGVARVIEHS ARVSENAAKL TTHMRSICDL LCEADYWADQ HGRELVNAED VQAAISAQIH
RGSRMKERLH EHIQRGILLI DSSGTAAGQV NGLSVIDLGN ISFGVPTRIT ARVRMGDGDV
LDIEREVDLG GPLHSKGVLI LAGFLGARFA KECPLALSAS LVFEQSYGEI EGDSASSAEL
YALLSALSGV PIKQGFAVTG SVNQHGQVQA IGGVNEKIEG FFDVCSERGL NGEQGVLIPP
SNVGDLMLRR DVIAAAEQGK FHIYAVETID QGIELLTGVP AGVPDAEGNY PHGSINHKVA
QQLLKFAEIR HEFGDLKKDH DDGAHHDKDD D
//
