ID A0A0S2W3S2_9FIRM Unreviewed; 375 AA.
AC A0A0S2W3S2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Cysteine desulfurase {ECO:0000313|EMBL:ALP94004.1};
DE EC=2.8.1.7 {ECO:0000313|EMBL:ALP94004.1};
GN ORFNames=IB211_01613 {ECO:0000313|EMBL:ALP94004.1};
OS Intestinimonas butyriciproducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Intestinimonas.
OX NCBI_TaxID=1297617 {ECO:0000313|EMBL:ALP94004.1, ECO:0000313|Proteomes:UP000064844};
RN [1] {ECO:0000313|EMBL:ALP94004.1, ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|EMBL:ALP94004.1,
RC ECO:0000313|Proteomes:UP000064844};
RX PubMed=26620920; DOI=10.1038/ncomms10062;
RA Bui T.P., Ritari J., Boeren S., de Waard P., Plugge C.M., de Vos W.M.;
RT "Production of butyrate from lysine and the Amadori product fructoselysine
RT by a human gut commensal.";
RL Nat. Commun. 6:10062-10062(2015).
RN [2] {ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|Proteomes:UP000064844};
RA de Vos W.M., Bui N.T.P., Plugge C.M., Ritari J.;
RT "A butyrogenic pathway from the amino acid lysine in a human gut
RT commensal.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011307; ALP94004.1; -; Genomic_DNA.
DR RefSeq; WP_058117689.1; NZ_CP011307.1.
DR AlphaFoldDB; A0A0S2W3S2; -.
DR STRING; 1297617.IB211_01613; -.
DR KEGG; ibu:IB211_01613; -.
DR PATRIC; fig|1297617.4.peg.1654; -.
DR eggNOG; COG0520; Bacteria.
DR Proteomes; UP000064844; Chromosome.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR43586; CYSTEINE DESULFURASE; 1.
DR PANTHER; PTHR43586:SF4; ISOPENICILLIN N EPIMERASE; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000064844};
KW Transferase {ECO:0000313|EMBL:ALP94004.1}.
FT DOMAIN 2..364
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 375 AA; 39851 MW; 9BC028B82514BB74 CRC64;
MIYLDAAATT LQKPSAVARA SGYAMGHMAS PGRGGHPPAM LAADTVFACR ERAAELFHVR
EPDDVVFTMN ATHGLNIAIK SIVKPGDTVL ISGYEHNAVT RPLAAIPNVR VKVATSRLFD
PQEILRQFRE QLTSEVDCVI CNHVSNVFGY VLPVVEIADL CAGRGVPFVL DASQSAGSMP
IYMDQLRASF IAMPGHKGLY GPQGTGILLC DHEVIPLLEG GTGSLSARQE MPDFLPDRLE
AGTQNVTGIA GLLEGLRFIQ RKSPEVILNH ERFLAARCAD ALSALPGVRV FAAPRLFCQA
GVLSFQVDGM DCEDVGQALG EQGIAVRSGL HCAPLAHRSA GTLDVGTVRV SFSAFNSSGD
VDALAGAVAR LPRRQ
//
