ID A0A0S2W669_9FIRM Unreviewed; 2087 AA.
AC A0A0S2W669;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=SLH domain-containing protein {ECO:0000259|PROSITE:PS51272};
GN ORFNames=IB211_02418 {ECO:0000313|EMBL:ALP94809.1};
OS Intestinimonas butyriciproducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Intestinimonas.
OX NCBI_TaxID=1297617 {ECO:0000313|EMBL:ALP94809.1, ECO:0000313|Proteomes:UP000064844};
RN [1] {ECO:0000313|EMBL:ALP94809.1, ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|EMBL:ALP94809.1,
RC ECO:0000313|Proteomes:UP000064844};
RX PubMed=26620920; DOI=10.1038/ncomms10062;
RA Bui T.P., Ritari J., Boeren S., de Waard P., Plugge C.M., de Vos W.M.;
RT "Production of butyrate from lysine and the Amadori product fructoselysine
RT by a human gut commensal.";
RL Nat. Commun. 6:10062-10062(2015).
RN [2] {ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|Proteomes:UP000064844};
RA de Vos W.M., Bui N.T.P., Plugge C.M., Ritari J.;
RT "A butyrogenic pathway from the amino acid lysine in a human gut
RT commensal.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall, S-layer
CC {ECO:0000256|ARBA:ARBA00004237}.
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DR EMBL; CP011307; ALP94809.1; -; Genomic_DNA.
DR RefSeq; WP_058118162.1; NZ_CP011307.1.
DR STRING; 1297617.IB211_02418; -.
DR KEGG; ibu:IB211_02418; -.
DR PATRIC; fig|1297617.4.peg.2488; -.
DR eggNOG; COG2234; Bacteria.
DR eggNOG; COG2866; Bacteria.
DR Proteomes; UP000064844; Chromosome.
DR GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.630.10; Zn peptidases; 2.
DR InterPro; IPR044060; Bacterial_rp_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR001119; SLH_dom.
DR PANTHER; PTHR43308:SF4; OUTER MEMBRANE PROTEIN ALPHA; 1.
DR PANTHER; PTHR43308; OUTER MEMBRANE PROTEIN ALPHA-RELATED; 1.
DR Pfam; PF18998; Flg_new_2; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF00395; SLH; 3.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 2.
DR PROSITE; PS51272; SLH; 3.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022601};
KW Reference proteome {ECO:0000313|Proteomes:UP000064844};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW S-layer {ECO:0000256|ARBA:ARBA00022601};
KW Secreted {ECO:0000256|ARBA:ARBA00022601}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..2087
FT /note="SLH domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006606361"
FT DOMAIN 1907..1965
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 1966..2029
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 2032..2087
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT REGION 1806..1848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1806..1844
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2087 AA; 228844 MW; 592E92016BCACC5A CRC64;
MKQRKKRLNK VLSMLLTLSM LLSMLVIPAA AADPISDYPD DLDAIVELLS GADGVDGESA
FDYLGTVFLG WRTTGGPWQN YVINDFVGQT MVDAGYVDKG DSTVTVDKDG NRTVENDWTH
DYGGDYFWVQ HDDSTSLVWA PEYARMEITS ITKGGQELDD TDPLYALRDV VNVESYAFDP
TSEIYQAHYN DVYSLGATPG DTDDFVKKMS GWINEKDSGG TRVNVFPYGE DPGDPRGPEA
HLNERAHLAT NAGFNVTENE LEAIRENPGD VRNLVAGKTG EVVYVGNVSK YTGDTSELAG
KILLCDSSNR TNFDFAQKVG AVSVMTTAAL SNFSNPIESE DWYGPEGAAA DWYDEWYDGK
NEWYTDSARF AGGRGADANK KAMDAGKPIV EWNISPDQYN ALRTLMDKGY TVEMNVATVG
EMYEMSGDHE GAQGQLTAIA EIKGSNPDLR HERVVLAAHV QEPGCDDNAT GVALNLELAV
KMKQLIDDGK IARPERTIVF MWGDEMSFSR LYLNAHPDEV DDIICCIDLD MVGEDPAKTG
GPMRIEKAPD PSAYYNYTLD NIPEDPLYYN PTRSDEDGNF VRLPDSHTLW GAGDPGDYDL
GGIFINDLYM ASAQSTRTVV ADTLGYDFQV DVCPYEGGSD HSRFLERGVP AVLTWHFTDY
VYHTTVDTLY MASADELESV GITSLSAGYF AANPTQYTNE MLEILVDAAA DRFASEAKEN
TEAHKAWADA TKSSVDDAYA LEVEVLKAWG DWYREAIASC TRYFSSSAEL AAPHLAEIDK
IETLALANAK AVFYGAGLAV NDSLLSLTEK DQAFVAALTV DAADLGATAP EEWAKTLSLS
LTREKSEQDP ELFPYCYTGD KLENWQTWGS NGSDGEKLFT IEPVEVIASG DKVTAVLRFT
ADHAFFKTSR SDGINTSSNR TAWMSIIGMY QFSVQSGEDT LATTDLMVNI YDDYTRYDDT
REKLAAIQKA AEANGRYMTV VENGKSEGGR DVYYAVFSDS KDSVDAFQAM NEIAETDPAS
LQTKIKDGTL EYRVPFMINN VHTDECPGVD GQLSFLYALA TQDSIDYRTL TGFLDESVDI
HELFAEDVVD LGITGLGSQK FTVDENGRIR NNTGVNDASE LYTIGDKSLD VDEVLDNIIF
IVQPTENPDG RAFNERRNAN GYDLNRDASN QTQAETRNLA AMINDWNPVV FAELHGFMTQ
FLVEPCTPPH EPNMEYDLLV KNFMLGAEAY GTAALGTISN EFEDTKFWSY YTPLRDDYDP
KTTTWSAWDD LCTNYGPSYA MLNCGTMGYT IETPYNNQAS SKLFEYGMYG LVDYVMENKD
DIYSNQLEFF RRGINNEDHR EDMESWYVDI SNKVLESDTW RVPYAGNDNY FPEYYVLPVD
AASQRDIANA YEMGEFLLHN GVKVSKLTED TKVGDVTYKA GSLIVDMYQA KRNYANAVLW
EGADASASGF PDLYSESVSN FPEMRGFDCI AIDTVGAFSG KLEELTEVTG KTEFTGSTSR
AVIISNNGNE AVRAINAMLD DGISVGLVTE GDYKGDFVVS YKDFALYRDE FILSATGVSD
MPVAYEISQP TLYLVGQYDS FSNYKVTTGY YAEWFKDGYG FYDYRNVRSN QRYNEDVFAY
VKQLGFKVTD DPAEADVIVG SSALNQGERG EATVAAVKAG TPYIASGSSP LSYIKNNLLT
DLTTSSLGME ALHQVEYPND SLTTASYAAD GDNVIYTVNC AVVTTLPEGA EVLIKAIDED
SFIAGCCLND DGTPIDGFVE AFAIERDGMD ITVFANSINN RTHQQDDYRF VTNTVYSKML
SDSRMSIPST GGSSGGSSSS SSSSVDISAG KGGSVTTSPK SPVKGDKVTV TVKPDSGFEL
DTITITDKSG KAISFINNGD GTYTYTQPDG TVTIKTTFKA TTTPDESGAD KFTDISGHWA
QDAIRYVVDR GLMNGVSDTA FSPNSTLTRS MLVTILHRLE GTPAASGNSF ADVASGTWYT
DAVSWAAANG IVTGYSDTQF GPDDSITREQ LAAILYRYAA YKGMDTSATA DLANFPDSGS
VSTWAGDSVK WAVSFGLISG KDDGRLDPLG TATRAEVATI LMRFLSR
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