ID A0A0S2W6R1_9FIRM Unreviewed; 441 AA.
AC A0A0S2W6R1;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:ALP95034.1};
DE EC=1.1.1.1 {ECO:0000313|EMBL:ALP95034.1};
GN ORFNames=IB211_02643c {ECO:0000313|EMBL:ALP95034.1};
OS Intestinimonas butyriciproducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Intestinimonas.
OX NCBI_TaxID=1297617 {ECO:0000313|EMBL:ALP95034.1, ECO:0000313|Proteomes:UP000064844};
RN [1] {ECO:0000313|EMBL:ALP95034.1, ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|EMBL:ALP95034.1,
RC ECO:0000313|Proteomes:UP000064844};
RX PubMed=26620920; DOI=10.1038/ncomms10062;
RA Bui T.P., Ritari J., Boeren S., de Waard P., Plugge C.M., de Vos W.M.;
RT "Production of butyrate from lysine and the Amadori product fructoselysine
RT by a human gut commensal.";
RL Nat. Commun. 6:10062-10062(2015).
RN [2] {ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|Proteomes:UP000064844};
RA de Vos W.M., Bui N.T.P., Plugge C.M., Ritari J.;
RT "A butyrogenic pathway from the amino acid lysine in a human gut
RT commensal.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011307; ALP95034.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S2W6R1; -.
DR STRING; 1297617.IB211_02643c; -.
DR KEGG; ibu:IB211_02643c; -.
DR PATRIC; fig|1297617.4.peg.2720; -.
DR eggNOG; COG1454; Bacteria.
DR Proteomes; UP000064844; Chromosome.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF83; HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR PROSITE; PS00913; ADH_IRON_1; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ALP95034.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000064844}.
FT DOMAIN 97..431
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 441 AA; 47279 MW; D5607460C8056A24 CRC64;
MPTFPDFRYP LCRRPLERKK CGRRWELSQG EDMISNAGEP CQRRRGEIHA VNGNLRNICS
SGGKFSAGAI FFHPPAILTA SRKRQAETME TFWIKPKLYF GPEPMAALDR LAGKRVLIVT
DAFLASSGLL DRVKNRLTGA VEIFDQVEPD PSLRLVAQGV RMLRDFGPDA VVAFGGGSPM
DCAKGMCWFS DRHPPLWCIP TTAGTGSEVT SFAVLTDTDQ GVKYPLVEED LLPEAAILDA
SLLEGVPPHV TADTGMDVLT HAAEAVAAKG ASPFSDALAE KAFALAYRRL PEAHAGSREA
KQDMLLASCM AGMAFNAAGL GVCHSMAHAL GGRFHVPHGR LNALLLPGVI QFNAVEQRTA
EKYARLAKLC GLAANPRALS SAVTRLRSGL KIPLKLPVPA QEFRAALPGL AAAALQDVCL
PGNPRPVTAG EIEAMLREIG G
//
