ID A0A0S2W7F1_9FIRM Unreviewed; 978 AA.
AC A0A0S2W7F1;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Glutamate synthase small chain {ECO:0000313|EMBL:ALP95257.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:ALP95257.1};
GN ORFNames=IB211_02866c {ECO:0000313|EMBL:ALP95257.1};
OS Intestinimonas butyriciproducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Intestinimonas.
OX NCBI_TaxID=1297617 {ECO:0000313|EMBL:ALP95257.1, ECO:0000313|Proteomes:UP000064844};
RN [1] {ECO:0000313|EMBL:ALP95257.1, ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|EMBL:ALP95257.1,
RC ECO:0000313|Proteomes:UP000064844};
RX PubMed=26620920; DOI=10.1038/ncomms10062;
RA Bui T.P., Ritari J., Boeren S., de Waard P., Plugge C.M., de Vos W.M.;
RT "Production of butyrate from lysine and the Amadori product fructoselysine
RT by a human gut commensal.";
RL Nat. Commun. 6:10062-10062(2015).
RN [2] {ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|Proteomes:UP000064844};
RA de Vos W.M., Bui N.T.P., Plugge C.M., Ritari J.;
RT "A butyrogenic pathway from the amino acid lysine in a human gut
RT commensal.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR EMBL; CP011307; ALP95257.1; -; Genomic_DNA.
DR RefSeq; WP_058118413.1; NZ_CP011307.1.
DR AlphaFoldDB; A0A0S2W7F1; -.
DR STRING; 1297617.IB211_02866c; -.
DR KEGG; ibu:IB211_02866c; -.
DR PATRIC; fig|1297617.4.peg.2949; -.
DR eggNOG; COG0493; Bacteria.
DR eggNOG; COG1145; Bacteria.
DR Proteomes; UP000064844; Chromosome.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR017701; Se_rdtase_YgfK.
DR NCBIfam; TIGR03315; Se_ygfK; 1.
DR PANTHER; PTHR43073; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR PANTHER; PTHR43073:SF2; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:ALP95257.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000064844}.
FT DOMAIN 878..908
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 978 AA; 107707 MW; 8112833FF2C32CB9 CRC64;
MSDIMRPIPF AQLMDWALTE YRQQKSLFGV CKLVRHENGQ ARPIFGEKIE APFGPAAGPN
TQLAQNIVAT YAAGARFFEL KTVQIMDGEA LSKCVAKPCI TAGDECYNCE WSTELTVPQA
YEEYVKAWFA CKLLAKELAL GDPDGFVFNM SVGYDLEGIK SPKIDAYLEG MKDASGSAVW
RTCMEWALDN TDRFEQVDAA YIRTVSPRVS CSITESTLHG CPPDEIERIA TYLITEKGLH
TYIKCNPTLL GYTFARKRLD SLGFDYVTFD DHHFAEDLQW TDAVPMFRRL MGLCAERKLE
FGVKLTNTFP VDVAAGELPS QEMYMSGRAL FPLTISLARR IAEEFEGGLR ISYSGGADVH
NVEALFAAGI WPITVATTIL KPGGYQRLSQ MGKLLMDCGS EPFRGVNAQA VAALAEQVES
DPYYRKPIKP LPERKMHRKV PLIDCFTAPC RDGCPIEQDI PAYLMAVSRG EYGQALEIIT
RRNALPFITG TICPHRCADK CMRNYYEESV WIREMKLRAA QGGYDALLSK QKARSAVSGK
KVAVVGGGPA GMAAAFFLGR EGVPVTLFEA TGALGGVVRH IIPEFRISSE AIDKDEALVR
AMGAEVRLNT YVGSYQELEE QGFTHVIFAT GAQKPGDPRL EYGDYVNFTE VLAALKAGNA
PTLGTDVAVI GGGNSAMDTA RAVKRLPGVE HVRLVYRRTR RYMPAEEEEL RLALEEGVEF
LELLAPKGVK DNILTCAVME LGAPDASGRR APVPTGRTQE LPCTTLIAAV GERIDESVDV
GPWPVIGDRR QGPATVVEAI ADAIQASRAI MEWETGTYTN QNICEDYNRP FMKKGDLCSD
CDGCADTRCL GCPTVCEVCA DVCPNRANVA VAVPGKRQRQ IVHVDGMCNE CGNCATFCPY
ESRPYRDKFT LFWSREDFDN SGNEGWLPAS GEDGGCLVRL DGQVREYQVD DSGCGLPEDL
RLLILAVQDN YGYLLREK
//
