GenomeNet

Database: UniProt
Entry: A0A0S3EVD1_9SPHN
LinkDB: A0A0S3EVD1_9SPHN
Original site: A0A0S3EVD1_9SPHN 
ID   A0A0S3EVD1_9SPHN        Unreviewed;       348 AA.
AC   A0A0S3EVD1;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   25-OCT-2017, entry version 13.
DE   RecName: Full=Epoxyqueuosine reductase {ECO:0000256|HAMAP-Rule:MF_00916};
DE            EC=1.17.99.6 {ECO:0000256|HAMAP-Rule:MF_00916};
DE   AltName: Full=Queuosine biosynthesis protein QueG {ECO:0000256|HAMAP-Rule:MF_00916};
GN   Name=queG {ECO:0000256|HAMAP-Rule:MF_00916};
GN   ORFNames=ATN00_02775 {ECO:0000313|EMBL:ALR19388.1};
OS   Sphingobium baderi.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=1332080 {ECO:0000313|EMBL:ALR19388.1, ECO:0000313|Proteomes:UP000056968};
RN   [1] {ECO:0000313|EMBL:ALR19388.1, ECO:0000313|Proteomes:UP000056968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DE-13 {ECO:0000313|EMBL:ALR19388.1,
RC   ECO:0000313|Proteomes:UP000056968};
RA   Cheng M., Meng Q., Yang Y., Chu C., Yan X., He J., Li S.;
RT   "A Two-component Flavoprotein Monooxygenase System MeaXY Responsible
RT   for para-Hydroxylation of 2-Methyl-6-ethylaniline and 2,6-
RT   Diethylaniline in Sphingobium baderi DE-13.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the conversion of epoxyqueuosine (oQ) to
CC       queuosine (Q), which is a hypermodified base found in the wobble
CC       positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
CC       {ECO:0000256|HAMAP-Rule:MF_00916}.
CC   -!- CATALYTIC ACTIVITY: Queuosine(34) in tRNA + acceptor + H(2)O =
CC       epoxyqueuosine(34) in tRNA + reduced acceptor. {ECO:0000256|HAMAP-
CC       Rule:MF_00916}.
CC   -!- PATHWAY: tRNA modification; tRNA-queuosine biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_00916}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00916}.
CC   -!- SIMILARITY: Belongs to the QueG family. {ECO:0000256|HAMAP-
CC       Rule:MF_00916}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP013264; ALR19388.1; -; Genomic_DNA.
DR   RefSeq; WP_062061849.1; NZ_CP013264.1.
DR   EnsemblBacteria; ALR19388; ALR19388; ATN00_02775.
DR   KEGG; sbd:ATN00_02775; -.
DR   KO; K18979; -.
DR   UniPathway; UPA00392; -.
DR   Proteomes; UP000056968; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0052693; F:epoxyqueuosine reductase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008616; P:queuosine biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00916; QueG; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR013542; DUF1730.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR004453; QueG.
DR   PANTHER; PTHR30002; PTHR30002; 1.
DR   Pfam; PF08331; DUF1730; 1.
DR   SUPFAM; SSF46548; SSF46548; 1.
DR   TIGRFAMs; TIGR00276; TIGR00276; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Complete proteome {ECO:0000313|Proteomes:UP000056968};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Iron {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Iron-sulfur {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Oxidoreductase {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Queuosine biosynthesis {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Reference proteome {ECO:0000313|Proteomes:UP000056968};
KW   tRNA processing {ECO:0000256|HAMAP-Rule:MF_00916}.
FT   DOMAIN      181    210       4Fe-4S ferredoxin-type.
FT                                {ECO:0000259|PROSITE:PS51379}.
FT   METAL       190    190       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000256|HAMAP-Rule:MF_00916}.
FT   METAL       193    193       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000256|HAMAP-Rule:MF_00916}.
FT   METAL       196    196       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000256|HAMAP-Rule:MF_00916}.
FT   METAL       200    200       Iron-sulfur 2. {ECO:0000256|HAMAP-Rule:
FT                                MF_00916}.
FT   METAL       243    243       Iron-sulfur 2. {ECO:0000256|HAMAP-Rule:
FT                                MF_00916}.
FT   METAL       246    246       Iron-sulfur 2. {ECO:0000256|HAMAP-Rule:
FT                                MF_00916}.
FT   METAL       250    250       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000256|HAMAP-Rule:MF_00916}.
SQ   SEQUENCE   348 AA;  37465 MW;  823A95DEAD709B0A CRC64;
     MPTQIETLEQ RLKRQAAQLG FAACAIASAD AAPMAGRRLR DWLNAGHHGD MLWMEERAEQ
     RGSPRGLWPD VRSVIMLGMS YAPGRDPLAL AKAGDRARIS VYAQGKDYHD TVKKGLKALA
     RWLVEQQGSA LKVFVDTAPV MEKPLAMAAG LGWQGKHSNL VSRTHGSWLF LGAIYSEIAL
     TPDEGEHDHC GSCTACQTAC PTDAFPSPYV VDARRCISYL TIEHKGPIPE ALRPGIGNRV
     YGCDDCLAVC PWNKFADAAA ANRAFLGRAE LAAPAIEDLL ALDDAAFREI FSGSPIKRIG
     RGRMVRNAAV AAGNSGEPRL IAKLRPLTSD GDPVVAEAAT WAIARLSA
//
DBGET integrated database retrieval system