ID   A0A0S3F2W2_9SPHN        Unreviewed;       360 AA.
AC   A0A0S3F2W2;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:ALR22057.1};
GN   ORFNames=ATN00_18855 {ECO:0000313|EMBL:ALR22057.1};
OS   Sphingobium baderi.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=1332080 {ECO:0000313|EMBL:ALR22057.1, ECO:0000313|Proteomes:UP000056968};
RN   [1] {ECO:0000313|EMBL:ALR22057.1, ECO:0000313|Proteomes:UP000056968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DE-13 {ECO:0000313|EMBL:ALR22057.1,
RC   ECO:0000313|Proteomes:UP000056968};
RA   Cheng M., Meng Q., Yang Y., Chu C., Yan X., He J., Li S.;
RT   "A Two-component Flavoprotein Monooxygenase System MeaXY Responsible for
RT   para-Hydroxylation of 2-Methyl-6-ethylaniline and 2,6-Diethylaniline in
RT   Sphingobium baderi DE-13.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP013264; ALR22057.1; -; Genomic_DNA.
DR   RefSeq; WP_062067719.1; NZ_CP013264.1.
DR   AlphaFoldDB; A0A0S3F2W2; -.
DR   STRING; 1332080.ATN00_18855; -.
DR   KEGG; sbd:ATN00_18855; -.
DR   OrthoDB; 4190732at2; -.
DR   Proteomes; UP000056968; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08231; MDR_TM0436_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR   PANTHER; PTHR43401:SF1; PKS_ER DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000056968};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          27..137
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          185..317
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   360 AA;  37988 MW;  14EE806C8F042F5E CRC64;
     MHGKAAVLVE KNRLETWDVE VRAPEPGGAL VRTILGGVCG SDVHILTGEA GEMPFPIILG
     HEGVGEITQL GAGVSTDYAG VPVKPGDLVI WSPIALCHRC YSCTILEQTP CENSQYFEDA
     SKPNWGSYSD YAWLPNNMPF YRLPDHAKPE AIAALGCALP TVLRGFDRCG PVRFGDSVVV
     QGAGPVGLSA VLVAAQAGAR EVIVIDGAPA RLEAAVKLGA TATVSLDLSP EERKRMIYDR
     IGRQGPDIVI EAAGALSAFP EGVDISGIHS RYIILGLWGA IGTQPISPRD LTLKNLTVGG
     ASFPAPKNYY QAMQFAARVQ GDVPLAQLVS HRFGISQAAE ALQVTKTGVA TKAVIDPTIS
//