ID   A0A0S3PTW9_9BRAD        Unreviewed;      1048 AA.
AC   A0A0S3PTW9;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Adenylate cyclase 2 {ECO:0000313|EMBL:BAT59385.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:BAT59385.1};
GN   Name=cyaB {ECO:0000313|EMBL:BAT59385.1};
GN   ORFNames=GJW-30_1_01918 {ECO:0000313|EMBL:BAT59385.1};
OS   Variibacter gotjawalensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Variibacter.
OX   NCBI_TaxID=1333996 {ECO:0000313|EMBL:BAT59385.1, ECO:0000313|Proteomes:UP000236884};
RN   [1] {ECO:0000313|EMBL:BAT59385.1, ECO:0000313|Proteomes:UP000236884}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GJW-30 {ECO:0000313|EMBL:BAT59385.1,
RC   ECO:0000313|Proteomes:UP000236884};
RA   Lee J.S.;
RT   "Investigation of the bacterial diversity of lava forest soil.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AP014946; BAT59385.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S3PTW9; -.
DR   KEGG; vgo:GJW-30_1_01918; -.
DR   OrthoDB; 9785312at2; -.
DR   Proteomes; UP000236884; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:BAT59385.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236884}.
FT   DOMAIN          20..152
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   1048 AA;  115292 MW;  6EF8BB85688C6CDE CRC64;
     MATSSTTARH EFAGERKHAT VLFADVAGFT AISERLGEEA AFEIIQSIRA MMREVVAEFS
     GTILDFAGDG LLAVFGVPKA LEDAPLSACR AALALLSRTV SAAPAYHARY GIDVQLRIGI
     NSGAVVVGHV EAQGGKQLTA VGDAVNVAAR LQARAEAGSI ILSDVIYQLV DDIAVVTPLG
     AFSLKGKSEA QHAFRLDALK HVATRFDRSV SRGLSQYVGR ENELRTIRDI VATKEGVSVV
     DIAGDPGMGK SRLLYEFRGN IDQARFVYLA GRCTREGQRT AFFPFIEIVR SWADIAIGED
     RRQTIKKLNE ALDALGLFTP DRLAILLNLT GQESASEQLA GLDPLQIGLR TRDLLIDLLR
     AACRMSPTIL TIEDLHWIDS SSESLLETIA SLQDIATLVV IHTRRSHYAP PWANATNVSS
     IPLAPLDSAQ IVEIVTSRLQ VQDISADFVE QIVRQADGNA LFAEEIAKFI GESAQARVQP
     AGRLPVSIQA ILGARIELLS DDQRRLLQIA SVFGRRFDIE QLAELLELPA DVVSREIEQA
     HRSELLHIDR RTGEAVFSHA LLNEVLYGGM LRTDRAVYHL KVAKTIEAKS GGTSENAELL
     THHYRQTDRH DRTLMFAAMA ARKSLRVYSL VEAEEFAKLA LEALTLSGRT NDAALPDLIA
     DYILVLQLGY NIPDLIKVAE LWLPRIDAPS LAKVSAMHHY ANALLLAGRY QDCKATSEKL
     DAISNELGDD RSKLYAFTVS VWIGALLATR SNEAIDAQAP AMFAAALRTT DIYLKIWLRW
     VLSLDAVHRG LLHSAYKYAQ ELIELGQTAK DSRATGLGLW LQGWNALIND DYALALKFGH
     EASAAALTPW DRSTAMNLTA SALVLTRQLD EGLALLKCRR DLDDAAGRRY AFVANDAVWG
     AGLVLSGKFR AGIRFIENRI EMREAEGYRS AADWYRVTLC YILLEVLQGG RRPQASVLIR
     NLPYLIWLKI TGLKRIDRLI ARARQNPLFH PEGLHQAKVH FIIGSRWRLA GRTELARKSL
     QEAKRIAKVF GDTPLAAKID ASLDEVMS
//