ID   A0A0S3PXY0_9BRAD        Unreviewed;       341 AA.
AC   A0A0S3PXY0;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=NADPH-dependent curcumin reductase {ECO:0000313|EMBL:BAT60791.1};
DE            EC=1.3.1.- {ECO:0000313|EMBL:BAT60791.1};
GN   Name=curA_1 {ECO:0000313|EMBL:BAT60791.1};
GN   ORFNames=GJW-30_1_03341 {ECO:0000313|EMBL:BAT60791.1};
OS   Variibacter gotjawalensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Variibacter.
OX   NCBI_TaxID=1333996 {ECO:0000313|EMBL:BAT60791.1, ECO:0000313|Proteomes:UP000236884};
RN   [1] {ECO:0000313|EMBL:BAT60791.1, ECO:0000313|Proteomes:UP000236884}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GJW-30 {ECO:0000313|EMBL:BAT60791.1,
RC   ECO:0000313|Proteomes:UP000236884};
RA   Lee J.S.;
RT   "Investigation of the bacterial diversity of lava forest soil.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AP014946; BAT60791.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S3PXY0; -.
DR   KEGG; vgo:GJW-30_1_03341; -.
DR   OrthoDB; 9805663at2; -.
DR   Proteomes; UP000236884; Chromosome.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd05288; PGDH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR041694; ADH_N_2.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR045010; MDR_fam.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR   PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR   Pfam; PF16884; ADH_N_2; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:BAT60791.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236884}.
FT   DOMAIN          18..334
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   341 AA;  36603 MW;  0B25F503B60F6862 CRC64;
     MAETHRRIIM TSRPKAEPTP DNFRLEEGPV PKAGAGEILV RTKYLSLDPY MRGRMSDAAS
     YAAPVEVGGL MQGELVGEVV SSDNEKFKVG EHIAGHLGWQ SHAVSNGKGL RKLDAGQPLA
     PSLGVLGMPG MTAYTGLLEI GQPKAGETVL VAAASGAVGQ LVGQIAKLKG ARAVGIAGGP
     EKCRYVVEEL GFDACIDHKA PGMAEHLKEA CPKGVDVYFE NVGGPVFEAV FPLFNFFARM
     PVCGLISQYN MTELPAGPNK VPQLFRAVLT KRLTIRGFIV WDFAAREADF RRDMAAWVKS
     GEIKHREHIV DGLENAPSAF IGLLRGENFG KTVVRVAPDA K
//