ID A0A0S3Q0P0_9BRAD Unreviewed; 510 AA.
AC A0A0S3Q0P0;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=tRNA threonylcarbamoyladenosine biosynthesis protein TsaE {ECO:0000256|ARBA:ARBA00019010};
DE AltName: Full=t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE {ECO:0000256|ARBA:ARBA00032441};
GN Name=tsaE {ECO:0000313|EMBL:BAT61730.1};
GN ORFNames=GJW-30_1_04291 {ECO:0000313|EMBL:BAT61730.1};
OS Variibacter gotjawalensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Variibacter.
OX NCBI_TaxID=1333996 {ECO:0000313|EMBL:BAT61730.1, ECO:0000313|Proteomes:UP000236884};
RN [1] {ECO:0000313|EMBL:BAT61730.1, ECO:0000313|Proteomes:UP000236884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GJW-30 {ECO:0000313|EMBL:BAT61730.1,
RC ECO:0000313|Proteomes:UP000236884};
RA Lee J.S.;
RT "Investigation of the bacterial diversity of lava forest soil.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TsaE family.
CC {ECO:0000256|ARBA:ARBA00007599}.
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DR EMBL; AP014946; BAT61730.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S3Q0P0; -.
DR KEGG; vgo:GJW-30_1_04291; -.
DR Proteomes; UP000236884; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0002949; P:tRNA threonylcarbamoyladenosine modification; IEA:InterPro.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR012180; Bifunc_ATPase/PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003442; T6A_TsaE.
DR NCBIfam; TIGR00150; T6A_YjeE; 1.
DR PANTHER; PTHR33540; TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE; 1.
DR PANTHER; PTHR33540:SF2; TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE; 1.
DR Pfam; PF01636; APH; 1.
DR Pfam; PF02367; TsaE; 1.
DR PIRSF; PIRSF036599; AtpPhos; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000236884};
KW Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT DOMAIN 180..428
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 510 AA; 56800 MW; 1089343B2F17F1D9 CRC64;
MLTMMQNAGT EIVLADEDAT RRLAADLSPA IGPGDLVALS GDLGAGKTAF ARALIRHLAG
EESIEVPSPT FTLVQTYDLP QFPLVHLDLY RLGHEDELLE LGIDELFAGA VTLVEWPDRG
GSQLPTPRMS IHFAMAPELG PQYRRVTLDI APPVPENIAK LLTFQRFLSE AGFGSAERVR
LQGDASTRIY DRLVDGERSA ILMIAPRRPD GPIVRDGKPY SQIAHLAEDV TPFVAMARGL
RERGLAAPEI MAADLDAGLL VLEDFGNEPV VSGNPPSPID ERYATAIDAL VSLHAHDLPG
TLPVAPGVQH RIPRYDIDAM MIEVELLLDW YLPQQSKQAT DEQREEYVAL WREALEPAMN
APATWVLRDF HSPNLMWREE RQGLDRLGIL DFQDALLGPA AYDVVSLLQD ARVDVPLSLE
DTLISRYMKG RRASDREFDL VQFVELYALM GAQRATKIVG IFARLDKRDG KPQYLRHQPR
VWRNMRRSLA HPSLAKLKAW YDENVPPLKA
//
