ID A0A0S3QTZ7_THET7 Unreviewed; 375 AA.
AC A0A0S3QTZ7;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Pyruvate ferredoxin oxidoreductase, alpha subunit {ECO:0000313|EMBL:BAT71795.1};
DE EC=1.2.7.1 {ECO:0000313|EMBL:BAT71795.1};
GN ORFNames=TST_1001 {ECO:0000313|EMBL:BAT71795.1};
OS Thermosulfidibacter takaii (strain DSM 17441 / JCM 13301 / NBRC 103674 /
OS ABI70S6).
OC Bacteria; Aquificota; Aquificae; Aquificales.
OX NCBI_TaxID=1298851 {ECO:0000313|EMBL:BAT71795.1, ECO:0000313|Proteomes:UP000063234};
RN [1] {ECO:0000313|Proteomes:UP000063234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17441 / JCM 13301 / NBRC 103674 / ABI70S6
RC {ECO:0000313|Proteomes:UP000063234};
RX PubMed=29420286; DOI=10.1126/science.aao3407;
RA Nunoura T., Chikaraishi Y., Izaki R., Suwa T., Sato T., Harada T., Mori K.,
RA Kato Y., Miyazaki M., Shimamura S., Yanagawa K., Shuto A., Ohkouchi N.,
RA Fujita N., Takaki Y., Atomi H., Takai K.;
RT "A primordial and reversible TCA cycle in a facultatively
RT chemolithoautotrophic thermophile.";
RL Science 359:559-563(2018).
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DR EMBL; AP013035; BAT71795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S3QTZ7; -.
DR STRING; 1298851.TST_1001; -.
DR KEGG; ttk:TST_1001; -.
DR PATRIC; fig|1298851.3.peg.1044; -.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000063234; Chromosome.
DR GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:BAT71795.1};
KW Pyruvate {ECO:0000313|EMBL:BAT71795.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000063234}.
FT DOMAIN 14..231
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 257..356
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 375 AA; 42080 MW; 2502A3890824C6D2 CRC64;
MKKLLTSAEA IAHALLLIKP EVISAYPITP QTPIIEKIAQ YVEAGMLDAE FVRVESEISA
LAVVIGSVAQ GIRAFTATSS QGLLYMHELL HWAAGGRLPI VMAVANRAVG APWNIWCDQQ
DMMAQRDTGW MQIYASNATE AQDFTVISYR VSEEVFIPTM VGIDGFILSH TAEPVDVLDY
KGVENFLPHL DFPLRLTHQE PFTLWPILEP ALYHRQRNDL FKDMKKAIEV WERAFSDFAK
LTGRKYYPVE EYGTDNAHTL FVCTGAIAET TKYVVKKLRE RGEKVGLATV KLLRPLPVDH
IRNLAVKAER LIVLDRAVSY GNEGILSQEI RAAISGAIPV YPCVVSMGGR EIYPRDLEEI
YTKTSRMNEG EVLWI
//
