ID A0A0S3QU08_THET7 Unreviewed; 346 AA.
AC A0A0S3QU08;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=2-oxoglutarate ferredoxin oxidoreductase subunit alpha {ECO:0000313|EMBL:BAT71810.1};
DE EC=1.2.7.3 {ECO:0000313|EMBL:BAT71810.1};
GN ORFNames=TST_1016 {ECO:0000313|EMBL:BAT71810.1};
OS Thermosulfidibacter takaii (strain DSM 17441 / JCM 13301 / NBRC 103674 /
OS ABI70S6).
OC Bacteria; Aquificota; Aquificae; Aquificales.
OX NCBI_TaxID=1298851 {ECO:0000313|EMBL:BAT71810.1, ECO:0000313|Proteomes:UP000063234};
RN [1] {ECO:0000313|Proteomes:UP000063234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17441 / JCM 13301 / NBRC 103674 / ABI70S6
RC {ECO:0000313|Proteomes:UP000063234};
RX PubMed=29420286; DOI=10.1126/science.aao3407;
RA Nunoura T., Chikaraishi Y., Izaki R., Suwa T., Sato T., Harada T., Mori K.,
RA Kato Y., Miyazaki M., Shimamura S., Yanagawa K., Shuto A., Ohkouchi N.,
RA Fujita N., Takaki Y., Atomi H., Takai K.;
RT "A primordial and reversible TCA cycle in a facultatively
RT chemolithoautotrophic thermophile.";
RL Science 359:559-563(2018).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP013035; BAT71810.1; -; Genomic_DNA.
DR RefSeq; WP_068549808.1; NZ_AP013035.1.
DR AlphaFoldDB; A0A0S3QU08; -.
DR STRING; 1298851.TST_1016; -.
DR KEGG; ttk:TST_1016; -.
DR PATRIC; fig|1298851.3.peg.1059; -.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000063234; Chromosome.
DR GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR43088; SUBUNIT OF PYRUVATE:FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR43088:SF1; SUBUNIT OF PYRUVATE:FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:BAT71810.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000063234}.
FT DOMAIN 15..184
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 248..321
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 346 AA; 38642 MW; 202037314C7552FF CRC64;
MSGKKLWKGC DAIAEAAIQA GCRFFAGYPI TPQSQILEYM SWRMFEVEGV FIQSESELAA
INMVMGAAIA GVRAMTASSS PGISLMQEGI SYMAGMELPA VIVNVNRGGP GLGGIQPNQG
DYFQSTRGGG HGDYRTLVLA PSTVQESVDC VFEAFNLADK YRNPVLIQID GIIAQMMESV
EISTHLYKPP PEKPWALTGC EGREPQFVKS LYLGPGELTQ HDWKLYRKYK GMEKEVKWEE
YLIDDEPDLL LVAFGTAARV SKTAIQWLKK EGKKVGLFRP ITLFPYPADA LRRASERAKK
IMVLEMNTGQ MLEDVERFTC KDVLFFGKPS DTFYPEEIYE KIKQIL
//
