ID A0A0S3SPF4_PHAAN Unreviewed; 406 AA.
AC A0A0S3SPF4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Auxin efflux carrier component {ECO:0008006|Google:ProtNLM};
GN Name=Vigan.08G132600 {ECO:0000313|EMBL:BAT94703.1};
GN ORFNames=VIGAN_08132600 {ECO:0000313|EMBL:BAT94703.1};
OS Vigna angularis var. angularis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=157739 {ECO:0000313|EMBL:BAT94703.1, ECO:0000313|Proteomes:UP000291084};
RN [1] {ECO:0000313|EMBL:BAT94703.1, ECO:0000313|Proteomes:UP000291084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shumari {ECO:0000313|Proteomes:UP000291084};
RX PubMed=26616024; DOI=10.1038/srep16780;
RA Sakai H., Naito K., Ogiso-Tanaka E., Takahashi Y., Iseki K., Muto C.,
RA Satou K., Teruya K., Shiroma A., Shimoji M., Hirano T., Itoh T., Kaga A.,
RA Tomooka N.;
RT "The power of single molecule real-time sequencing technology in the de
RT novo assembly of a eukaryotic genome.";
RL Sci. Rep. 5:16780-16780(2015).
CC -!- FUNCTION: Involved in cellular auxin homeostasis by regulating auxin
CC metabolism. Regulates intracellular auxin accumulation at the
CC endoplasmic reticulum and thus auxin availability for nuclear auxin
CC signaling. {ECO:0000256|ARBA:ARBA00025100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
CC {ECO:0000256|ARBA:ARBA00025752}.
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DR EMBL; AP015041; BAT94703.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S3SPF4; -.
DR Proteomes; UP000291084; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0080162; P:endoplasmic reticulum to cytosol auxin transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR045033; PILS1/3/4/5/7.
DR PANTHER; PTHR31651:SF45; AUXIN EFFLUX CARRIER FAMILY PROTEIN; 1.
DR PANTHER; PTHR31651; TRANSPORTER; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291084};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 406 AA; 44322 MW; 37F5CD0B9725925D CRC64;
MELWKLFTTA LMPVLKVLII TGLGTFLALH RFNILRESAR KHLNALVYFV FTPALICSIL
AKTITFKSLA MVWFMPLNIL LTFIIGTALG WLCLKITKAA PDMQGLVLGC CAAGNQGNMP
LIIIPAVCKE SGSPFGAVNV CNTKGMSYAS LSMAISNIYI WTFVYQIIRV YSCRNFNVNK
VDSPTVGPVS AIEADLENHS STPEVTAPQT NDLVTPFKTD TVSKEKQITK PLRTLVKRLN
LKILLAPPTL GSFVGLIIGV VPPFKKMFVG DDAPFRVVED SASMLGDACI PAMTLLVGAN
LLNGLKRSGL KPSVLVGIIV VRYIALPIFG VFIVKGAIRY GIIHQDPLYH FILLLQYALP
PAISISTITQ LFGAGETECS IVMLVTNVCA SFTLTLWSTF FMWLVL
//
