ID A0A0S3T4D6_PHAAN Unreviewed; 857 AA.
AC A0A0S3T4D6;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Vigan.10G120500 {ECO:0000313|EMBL:BAT99698.1};
GN ORFNames=VIGAN_10120500 {ECO:0000313|EMBL:BAT99698.1};
OS Vigna angularis var. angularis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=157739 {ECO:0000313|EMBL:BAT99698.1, ECO:0000313|Proteomes:UP000291084};
RN [1] {ECO:0000313|EMBL:BAT99698.1, ECO:0000313|Proteomes:UP000291084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shumari {ECO:0000313|Proteomes:UP000291084};
RX PubMed=26616024; DOI=10.1038/srep16780;
RA Sakai H., Naito K., Ogiso-Tanaka E., Takahashi Y., Iseki K., Muto C.,
RA Satou K., Teruya K., Shiroma A., Shimoji M., Hirano T., Itoh T., Kaga A.,
RA Tomooka N.;
RT "The power of single molecule real-time sequencing technology in the de
RT novo assembly of a eukaryotic genome.";
RL Sci. Rep. 5:16780-16780(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; AP015043; BAT99698.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S3T4D6; -.
DR Proteomes; UP000291084; Chromosome 10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF98; TO DEHYDRATION PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291084};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 573..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..178
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 199..361
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 372..644
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 736..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..755
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 782..813
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 97979 MW; 9518692F69A858D4 CRC64;
MATLADIGVS ATINILSAFA FLLAFALLRI QPINDRVYFP KWYLSGGRNS PRSSGNFVGK
FVNLNFKTYL TFLNWMPQAL RMSESEIISH AGLDSAAFLR IYTLGLKIFV PITIVALLIL
IPVNVSSGTL FFLKKELVVS DIDKLSISNV PTESIRFFVH IALEYLFTLW ICFLLYKEYD
YVATMRLHFM ASQRRRVEQF TVVVRNIPHM PGHAVSDSVE GFFKTNHPDH YIGHQAVYNA
NKFAKLAKRR ERLQNWLDYY QLKSERHPGK RSTVKTGLFG LWGGKVDAVE YYKHAIKELD
NVMTLERQKI IKDPKAILPV AFLSFNSRWG ASVCAQTQQS KNPTLWLTDW APEPRDVYWR
NLAIPFVSLS IRRLVISLSV FALVFFYMIP IAFVQSLANL DGLEKVAPFL RPVIEFNFIK
SFLQGFLPGL ALKVFLYILP TVLMIMSKIE GYIALSTLER KTAAKYYYFM LVNVFLGSIV
TGTAFQQLHA FLHQSPTQIP RTIGVSIPMK ATFFITYIMV DGWAGIAGEI LRLKPLVIYH
LKNMFIVKTE RDRGKAMNPG SVDFPETIPS LQLYFLLGIV YAVVTPILLP FILVFFAFAY
LVYRHQIINV YNQQYESAAA FWPLVHSRII ASMLISQFLL LGLLSTKKAA KSTPLLVILP
ILTFAFHKYC QRRFEPAFRK YPIEEAMSKD MLEKSTEPDL NIKAYLADAY LHPIFRSFEV
EEEELIEVRV DKHQTNVAAA SSPSSEPSSP SPPHHLHQSL PVHHLHLPSP PHHLHEPSPP
DHLHLQSPPP HHLPESSSPP HHLPEPSLPH HLPELIPPNH HLHEPSLPFP PPPYNEYPPG
YYYQYHLPSP PHHVYQY
//
