ID A0A0S3TBX6_PHAAN Unreviewed; 900 AA.
AC A0A0S3TBX6;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN Name=Vigan.11G221500 {ECO:0000313|EMBL:BAU02658.1};
GN ORFNames=VIGAN_11221500 {ECO:0000313|EMBL:BAU02658.1};
OS Vigna angularis var. angularis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=157739 {ECO:0000313|EMBL:BAU02658.1, ECO:0000313|Proteomes:UP000291084};
RN [1] {ECO:0000313|EMBL:BAU02658.1, ECO:0000313|Proteomes:UP000291084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shumari {ECO:0000313|Proteomes:UP000291084};
RX PubMed=26616024; DOI=10.1038/srep16780;
RA Sakai H., Naito K., Ogiso-Tanaka E., Takahashi Y., Iseki K., Muto C.,
RA Satou K., Teruya K., Shiroma A., Shimoji M., Hirano T., Itoh T., Kaga A.,
RA Tomooka N.;
RT "The power of single molecule real-time sequencing technology in the de
RT novo assembly of a eukaryotic genome.";
RL Sci. Rep. 5:16780-16780(2015).
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
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DR EMBL; AP015044; BAU02658.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S3TBX6; -.
DR Proteomes; UP000291084; Chromosome 11.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10218:SF317; EXTRA-LARGE GUANINE NUCLEOTIDE-BINDING PROTEIN 3-LIKE; 1.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000291084};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT DOMAIN 1..21
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 97..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 900 AA; 101312 MW; 73BA1BB47508C5F8 CRC64;
MASESTEEDK SWEHVLRRML PAGAPLPDEE HLDYSIAVEY EGPPVPYDVP KVDPLEIGAT
ASAVAVPIRT ASIVSDHNAS ASIPVAMPVH PRFSRFGRVR NGGFDRAPPP PPPRSPVESR
RSSSVSRSQS QFDSRSGEVV YRSDYSGEVN DEDGPSSASE ASEQQSPPNS APVPRSGAGA
GKRPTTVTFH TPRDSEDDDG DDFTSPRSVA TEPVGSPVGA SPSRNKKRWI CSRCGNSNRL
KEKEACLVCD SRYCSNCVLK AMGSMPEGRK CVSCIGKPID ESKRPSLGKC SRMLSKVCSS
LEINQIMKAE KECPANQLRP EQLIVNGRQL RQEELAEILG CPIPPQKLKP GRYWYDKDSG
LWGKEGEKPD KIISSKLNIG GKLQTDASNG NTRVYMNGRE ITKIELRMLK LANVQCPRDT
HFWVYEDGSY EEEGQNNIKG NIWGKASTRF ICSLFSLPVP PANPPGVRDN STNYSTRSVP
EYLEQGRVQK LLLFGMEGSG TATLFKQAKF LYGNKFSTEE LQNIKLMIQS NMYKYLSILL
EGREQFEEEA LAERESTSLE GEGSGQVQET AADGNKPSIY SINQRFKHFS DWLLDIMATG
DLEAFFPAAT REYAPMVDEI WRDPAVQETY KRREELHNLP DVAKYFLDRA IEISSNEYEP
SDKDVLYAEG VTQSNGLAFM EFSFDDRSPM SEIYSENLNC PPPLTKYQLI RINSKGLRDG
CKWLEMFEDV RAIIFCVALS DYDQMWPSSN GQLRNKLLAS KDLFESLVKH PCFKDTPFVL
LLNKYDAFED KINKVSLSTC EWFGDFCPVR PHHNNHALAH QAYYYVAVKF KELYYSLTGQ
KLFVGQTRGR DRTSVDEAFK YIREIIKWDD EKDDDVYEIN PEESSFYSTE MSSSPFVRQE
//
