ID   A0A0S4J5L7_BODSA        Unreviewed;       692 AA.
AC   A0A0S4J5L7;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   08-NOV-2023, entry version 32.
DE   SubName: Full=Mismatch repair protein, putative {ECO:0000313|EMBL:CUG84070.1};
GN   ORFNames=BSAL_88300 {ECO:0000313|EMBL:CUG84070.1};
OS   Bodo saltans (Flagellated protozoan).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Eubodonida; Bodonidae; Bodo.
OX   NCBI_TaxID=75058 {ECO:0000313|EMBL:CUG84070.1, ECO:0000313|Proteomes:UP000051952};
RN   [1] {ECO:0000313|Proteomes:UP000051952}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lake Konstanz {ECO:0000313|Proteomes:UP000051952};
RG   Pathogen Informatics;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC       {ECO:0000256|ARBA:ARBA00006082}.
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DR   EMBL; CYKH01001110; CUG84070.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S4J5L7; -.
DR   VEuPathDB; TriTrypDB:BSAL_88300; -.
DR   OMA; RTCKRER; -.
DR   OrthoDB; 4698638at2759; -.
DR   Proteomes; UP000051952; Unassembled WGS sequence.
DR   GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.1540.20; MutL, C-terminal domain, dimerisation subdomain; 1.
DR   Gene3D; 3.30.1370.100; MutL, C-terminal domain, regulatory subdomain; 1.
DR   InterPro; IPR014762; DNA_mismatch_repair_CS.
DR   InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR038973; MutL/Mlh/Pms-like.
DR   InterPro; IPR014790; MutL_C.
DR   InterPro; IPR042120; MutL_C_dimsub.
DR   InterPro; IPR042121; MutL_C_regsub.
DR   InterPro; IPR037198; MutL_C_sf.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR   PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR   PANTHER; PTHR10073:SF52; MISMATCH REPAIR ENDONUCLEASE PMS2; 1.
DR   Pfam; PF01119; DNA_mis_repair; 1.
DR   Pfam; PF08676; MutL_C; 1.
DR   SMART; SM01340; DNA_mis_repair; 1.
DR   SMART; SM00853; MutL_C; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF118116; DNA mismatch repair protein MutL; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR   PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051952}.
FT   DOMAIN          166..289
FT                   /note="DNA mismatch repair protein S5"
FT                   /evidence="ECO:0000259|SMART:SM01340"
FT   DOMAIN          497..647
FT                   /note="MutL C-terminal dimerisation"
FT                   /evidence="ECO:0000259|SMART:SM00853"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          333..400
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          441..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        333..348
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   692 AA;  75831 MW;  3356F0F0BD832E98 CRC64;
     MSKRVSSKRR RPTTQPSSSG ETASVDDDGG VEASSVDSLG FRGEALHSLA QLSDLVIDTM
     SMSATSGVTL THSVETNTTT VSASVTRTSH GTTVSSSNLF ARFPVRRGEL QRTKKKQLQD
     TIQLIKQYAL SRPDVKLILQ HRLDAADGAV VTLVSTSGSG DLQRSLGEAY GGRIVGSMMH
     VHWASLPHCE VSGYIAPVGG GRTTSDMQVF ALDGRVVDLP KLAKTLHDTF LEAHPNAAQR
     TCPAYFLSLK TDGTAAYDVN LAPNKRRVLL QLEREWVEAL RREALRMFKT STDAMEITAA
     TKNAVARDLA RADERRLSLT LTPVSATSHA QVILSADRRS GSDSLQPSGS LRKRERDDGA
     PLGLGMSLPP DRRLLLDDDD DRDVEVTSNS VVDTGAEEEG DEQMIVTDEG LLDYYLHRRT
     ARFESRFPDL SSLPASMVTE GASQSVESVE QSSGNKKNKT TTKGGNKPKK ISKSINAQTD
     DELNQMLHKT DFEKMEIHGQ FNHGFIVASL GEDLYIIDQH ASDEKFNYEQ LCQKYVARPQ
     PLVKPIRVAM EADEALLALE RAAELRAHGF IVQRPPDHDG APGGSNNLAV TVASVPILPY
     DTVVPQDVCE LTAQLLQYQS IVRPLKAVWH SMATKACRSS IMIGAVLNDK MMRTIVDHLG
     TLDQPWNCPH GRPTLRYLGS LATFRDDHQR ID
//