ID A0A0S4KPB8_9BACT Unreviewed; 544 AA.
AC A0A0S4KPB8;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Folate/biopterin family MFS transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=NITINOP_0160 {ECO:0000313|EMBL:CUQ65136.1};
OS Candidatus Nitrospira inopinata.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Nitrospira.
OX NCBI_TaxID=1715989 {ECO:0000313|EMBL:CUQ65136.1, ECO:0000313|Proteomes:UP000066284};
RN [1] {ECO:0000313|Proteomes:UP000066284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Daims H.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN885086; CUQ65136.1; -; Genomic_DNA.
DR RefSeq; WP_062481893.1; NZ_LN885086.1.
DR AlphaFoldDB; A0A0S4KPB8; -.
DR STRING; 1715989.NITINOP_0160; -.
DR KEGG; nio:NITINOP_0160; -.
DR OrthoDB; 9764193at2; -.
DR Proteomes; UP000066284; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF0; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR Pfam; PF03092; BT1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000066284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..536
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 544 AA; 59809 MW; 27C31FE75BD88382 CRC64;
MNTGLFQWID RNILSLGREM RFSYLPPLMV YMAYGISGLT GIVGTFFVKD YLGLSASFLA
ALGFWAGIPW ALKMPIGHTV DLLWRWKGWL VGLGACLLAA SLSIMAALIG QRDAMTAILP
AEVWFVISVL LAPIGYVIQD AVADAMTVEA VPRVNERGLP FSEEERKLMH TTMQTLGRVA
IVGGGIIVAL VNVSIFSGTE GLPQEALVTI YQRVYLSALV IPFISVLGLA AAWVIRRRHR
EQLIRQGFTV EQAERMVEVR ERAEEATKPN WWILAGSLLF VLFTVTVGMS SLPYREEIVF
AGSMGIVLFL MGRLVKELEP DKRMTLVGTA VVVFVFRAIP GTGPGTTWWM IDHLRFDQQF
LSVLSLIGNT LALVGMFVFR RFMAERSIAY VVGFLTIVGS VLSLPVVSMY YGLHEWTARM
TGGVVDARFI AIIDTALESP LGQISMIPML TWIANSAPAN LKATFFAVMA SFTNLALSLS
QLGTKYLNEI FVVTREVRDA TTGGIQVPAD YSRLGHLLVA QLLLGLALPL AAILFAKISR
FKSA
//
