ID A0A0S4KUT3_9BACT Unreviewed; 519 AA.
AC A0A0S4KUT3;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=NADH-quinone oxidoreductase, membrane subunit M {ECO:0000313|EMBL:CUQ66091.1};
DE EC=1.6.5.11 {ECO:0000313|EMBL:CUQ66091.1};
GN Name=nuoM {ECO:0000313|EMBL:CUQ66091.1};
GN ORFNames=NITINOP_1116 {ECO:0000313|EMBL:CUQ66091.1};
OS Candidatus Nitrospira inopinata.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Nitrospira.
OX NCBI_TaxID=1715989 {ECO:0000313|EMBL:CUQ66091.1, ECO:0000313|Proteomes:UP000066284};
RN [1] {ECO:0000313|Proteomes:UP000066284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Daims H.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009025}.
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DR EMBL; LN885086; CUQ66091.1; -; Genomic_DNA.
DR RefSeq; WP_062483888.1; NZ_LN885086.1.
DR AlphaFoldDB; A0A0S4KUT3; -.
DR STRING; 1715989.NITINOP_1116; -.
DR KEGG; nio:NITINOP_1116; -.
DR OrthoDB; 9805769at2; -.
DR Proteomes; UP000066284; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR NCBIfam; TIGR01972; NDH_I_M; 1.
DR PANTHER; PTHR43507:SF1; NAD(P)H-QUINONE OXIDOREDUCTASE CHAIN 4, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:CUQ66091.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000066284};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..433
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 519 AA; 57115 MW; 2A4CD7A2F3A7C838 CRC64;
MLEELTAGFP ILSCILFLPM AGAILLWLME DEDLVRTSAL AISLIELALA VFVLLRFVPE
SAAMQFAERV QWVPALGISY HLGVDGISVL FVGLTAFLTV LVVIYSWDTV RYQLKLYMMC
LLALETTTMG VFVSLDLVLF FVFWELMLIP SYFLIKLWGG GAERHYAALK FVLYTLLGSV
FLLVGIALLN INFHQWASLH HAEQAYSFDL LELLSVPVPY NQQVLIFWLM FMGFAFKAPL
FPFHTWLPDA LLEGPIGMAV VLAGVKLGTF GFIRFSIPLL PDASKSEPVV MVVVLLGLCA
ILYGAWIALI QHDLRRLLAY SSISHLGFVV VGLFALNYQG LQGSLLTMIN LGFSTAGLFF
IAGFLYSRQQ TTQLSSFGGM AKQVPLLATF FLIIGLASIG LPGTNGFVGE FLILMGAFKA
KWWIGAIAVL GVIFGAAYFL WYYERAMLGP AGKAVKSTMS DLQFREIVIA SALSVMIVWI
GLYPSPFLRI MNGSVQALVD RLNHGTVAAF ETAVGENGP
//
