ID A0A0S4L436_9BACT Unreviewed; 889 AA.
AC A0A0S4L436;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Methyl-accepting chemotaxis protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=COMA2_10130 {ECO:0000313|EMBL:CUS31485.1};
OS Candidatus Nitrospira nitrificans.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Nitrospira.
OX NCBI_TaxID=1742973 {ECO:0000313|EMBL:CUS31485.1, ECO:0000313|Proteomes:UP000198736};
RN [1] {ECO:0000313|Proteomes:UP000198736}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Luecker S., Luecker S.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CZPZ01000001; CUS31485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S4L436; -.
DR STRING; 1742973.COMA2_10130; -.
DR OrthoDB; 9765776at2; -.
DR Proteomes; UP000198736; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd19411; MCP2201-like_sensor; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR024478; HlyB_4HB_MCP.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR047347; YvaQ-like_sensor.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF12729; 4HB_MCP_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF08447; PAS_3; 2.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SMART; SM00086; PAC; 2.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198736};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 213..265
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 350..402
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 472..524
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 577..806
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 585..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 824..889
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 826..841
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..861
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 889 AA; 97200 MW; D3E79AC879F871B1 CRC64;
MNKFDNLTTG KKLLVGFGGI LAFFLVLGVF SIGGIRWVSD RTESIYKINL VPIKMLGDLR
ERTQRMSAYV SWHILAYDSA TVTKQAEAIA KTDEEITELV KSYDHVIVSE AERKYVEQFT
AGLSEYKEVR GKVLELSKNF SKDAAAELQK TQLAEKLEKI HDAVEGLIKE NEQQAKDSFE
VSQTVSWSAT MAVIVFCLLA GAVGVFGSMK VTRFIVGGLN DVLKATQELQ KGNLAHRSGL
HTNEEIGQLA LAFNQMAGAL EQAAAKQAEA LSAQAAEITG ITTAISKSRA VIEFNLDGTV
ITANDNFLQC LGYGLDEIKG RHHRMFCDPV HVNSGEYADF WQKLGRGEYV AGVYPRLRKD
GKEVWLQTSY NPILDANGRT YKVIEHATDI TAQKLAALES EGLLKAVDRG QAAIEFNMDG
TVRNANGLFL NLLGYGLNEV KGQHHRMFCD PVFTSSAEYT EFWKKLNNGE FHDGVYRRFG
KGNKEVWIQA TYNPIFDLKG KPYKVVKFAT DITAQKTGAM EMERLVQEAQ GVLGRLASND
LTQNMTETYV GDLEKIKVSI NAVVHNLNKT IISVRDAVDA VSSGSEQITK GSEDLSQRTS
EQASALEETS ASMEEMTSTV KQNADNAKQA NQLAIAARDT ADKGGAVTKK AVEAMGEINQ
SSKKIADIIT VIDEIAFQTN LLALNAAVEA ARAGEHGRGF AVVAAEVRNL AQRSATAAKE
IKGLINESIQ RVTDGSELVH QSGKTLEEIV TSVKRVTDII AEISAASQEQ ASGIDEVNKA
IVSMDGTTQQ NAALVEETTS AAQSMKEQAR ELMRQVEVFK ISGTRDASRP TVSSSKFHVS
SNRKNPHPET RNPKRETPGR ATLRPAELSG VATGNGKDRR SSGDEFEEF
//
