ID A0A0S4L895_9BACT Unreviewed; 351 AA.
AC A0A0S4L895;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Magnesium transport protein CorA {ECO:0000256|RuleBase:RU362010};
GN Name=corA {ECO:0000256|RuleBase:RU362010,
GN ECO:0000313|EMBL:CUS33423.1};
GN ORFNames=COMA1_11149 {ECO:0000313|EMBL:CUS33423.1};
OS Candidatus Nitrospira nitrosa.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Nitrospira.
OX NCBI_TaxID=1742972 {ECO:0000313|EMBL:CUS33423.1, ECO:0000313|Proteomes:UP000199032};
RN [1] {ECO:0000313|EMBL:CUS33423.1, ECO:0000313|Proteomes:UP000199032}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COMA1 {ECO:0000313|EMBL:CUS33423.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mediates influx of magnesium ions.
CC {ECO:0000256|RuleBase:RU362010}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362010}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362010}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU362010}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CZQA01000001; CUS33423.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S4L895; -.
DR OrthoDB; 9803416at2; -.
DR Proteomes; UP000199032; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd12828; TmCorA-like_1; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR004488; Mg/Co-transport_prot_CorA.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR NCBIfam; TIGR00383; corA; 1.
DR PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU362010};
KW Ion transport {ECO:0000256|RuleBase:RU362010};
KW Magnesium {ECO:0000256|RuleBase:RU362010};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362010};
KW Reference proteome {ECO:0000313|Proteomes:UP000199032};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362010};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362010}; Transport {ECO:0000256|RuleBase:RU362010}.
FT TRANSMEM 289..313
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362010"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362010"
SQ SEQUENCE 351 AA; 40114 MW; FAC0ED985D6C790E CRC64;
MKLVQKRSKK TGLSPGTLIH IGETRTNSVT VTRFNYAGTH CDEQVVTDME TLRPPADETV
TWVNVGGVHK VEVLEGFGKH FGLHPLLLED IANTDQRPKL DDYETYLFLV MKMLMTSDRG
DILVEQVSFV LGRNYVLSFQ ENGTDVFGAV RDRLKGGKGR LRQNGSDYLM YALIDAVVDQ
YFTVLEMLGE RIESLQERVI ADPKPETLQD IHALKRQLLF VRRAVWPLRE AMNNLSRSEC
PFLHEPMKLF FRDVYDHVVQ IVDTIETLRE MVSASLDIYL SSVSYRLNAV MRVLTVITTI
FMPLSFIAGI YGMNFEHMPE LKWAWGYPMA LGIMGIVAAI MLIGFRLKKW L
//
