ID   A0A0S4LHN9_9BACT        Unreviewed;       634 AA.
AC   A0A0S4LHN9;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Capsular polysaccharide biosynthesis protein CapD {ECO:0000313|EMBL:CUS36104.1};
GN   Name=capD {ECO:0000313|EMBL:CUS36104.1};
GN   ORFNames=COMA2_200063 {ECO:0000313|EMBL:CUS36104.1};
OS   Candidatus Nitrospira nitrificans.
OC   Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC   Nitrospira.
OX   NCBI_TaxID=1742973 {ECO:0000313|EMBL:CUS36104.1, ECO:0000313|Proteomes:UP000198736};
RN   [1] {ECO:0000313|Proteomes:UP000198736}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Luecker S., Luecker S.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; CZPZ01000013; CUS36104.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S4LHN9; -.
DR   STRING; 1742973.COMA2_200063; -.
DR   Proteomes; UP000198736; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198736};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        63..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          300..582
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   634 AA;  69818 MW;  77195EC39F97F99E CRC64;
     MRHMTIRLFH RTADRYGELV RGYRSLLVVG VQLGLIVAAN LSAFELRFDA EIPASYDRLM
     WRYLPGLVLV FGSSFWVFGI QRGLWRYVGL HDFGRIFAAS FTAAITFYGL CHLILGWAEY
     PRSVIILTGL LTGLYLAGIR VAVRWFREWL RLVGTTARRV LIIGAGHAGE LLARDILSDA
     GYNSRPVGFV DDDPIKRRMK IHGIPVVGMI ADIKTAAETL EAHEIIVAIP SASTTVKQKI
     LAASEGCTVP IKTLPNVKQL LGDPVSLHHV RPMSLDDLLQ REPIQTNLQE LSPLIAGKRL
     LVTGAGGSIG AELCRQIARY DPQSLVLFER YENALHALLL ELKTAFPALK IVPVIGDVTV
     PDRVSEVFQQ AGPDIVFHAA AHKHVPLMEL NPKEAIRNNV LGTRVVAEAA LKAGVDRFVL
     ISTDKAVNPS SIMGATKRIA EHVVQEFNRT GLTKFTVVRF GNVLGSNGSV VPLFSEQIRK
     GGPVTVTHPE IKRFFMTIPE AVQLVLQASV MGQGGEVFVL DMGEQIKIVD LARNMIVLAG
     LVPNKDIQLV FTGLRSGEKL YEELFEDGEQ VAPTTHPKIH RAGGAPVSTG ELDDWLESLE
     GNLPKCDEDT LLHDLKRLVP SFDSAPIQRV SDRR
//