ID   A0A0S4LNR3_9BACT        Unreviewed;       517 AA.
AC   A0A0S4LNR3;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Putative Exopolyphosphatase {ECO:0000313|EMBL:CUS37579.1};
DE            EC=3.6.1.11 {ECO:0000313|EMBL:CUS37579.1};
GN   ORFNames=COMA1_40122 {ECO:0000313|EMBL:CUS37579.1};
OS   Candidatus Nitrospira nitrosa.
OC   Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC   Nitrospira.
OX   NCBI_TaxID=1742972 {ECO:0000313|EMBL:CUS37579.1, ECO:0000313|Proteomes:UP000199032};
RN   [1] {ECO:0000313|EMBL:CUS37579.1, ECO:0000313|Proteomes:UP000199032}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COMA1 {ECO:0000313|EMBL:CUS37579.1};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CZQA01000010; CUS37579.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S4LNR3; -.
DR   STRING; 1742972.COMA1_40122; -.
DR   OrthoDB; 9814545at2; -.
DR   Proteomes; UP000199032; Unassembled WGS sequence.
DR   GO; GO:0004309; F:exopolyphosphatase activity; IEA:UniProtKB-EC.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR048950; Ppx_GppA_C.
DR   InterPro; IPR003695; Ppx_GppA_N.
DR   InterPro; IPR030673; PyroPPase_GppA_Ppx.
DR   PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR   PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR   Pfam; PF02541; Ppx-GppA; 1.
DR   Pfam; PF21447; Ppx-GppA_III; 1.
DR   PIRSF; PIRSF001267; Pyrophosphatase_GppA_Ppx; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:CUS37579.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199032}.
FT   DOMAIN          25..309
FT                   /note="Ppx/GppA phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02541"
FT   DOMAIN          322..463
FT                   /note="Ppx/GppA phosphatase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21447"
SQ   SEQUENCE   517 AA;  57479 MW;  62E6811AC7683B42 CRC64;
     MSKLAVIDIG TNSIHMVLAE VLPDASFKIL DRFKDITRLG NGVFATKRLS DESLARAMTV
     LKTLVTLARN KGFERIIAVA TSAVRESQNG GEFVAMILEQ IGLRVRVISG VEEARLIFLG
     VKNSIALPDG ATLVVDIGGG SVELIVGNRE GLMHGTSLKL GAIRLTEQCL TKSPPSESMM
     RALETVVTTH LRDAFGSFKM KKFHSLVATS GMAGNVGEVI HLRQTGRPLP QHNLATVPLK
     HIRSLEAELA RSSVKDRLAI PGLDPKRVDT LLPTTVVLRC LLELSGLQEI TLCDKAIREG
     VIYDFIARHR EGLKAEQDFP DVRRRNVIGL ARRCHAPEAH SLHVANLALQ LFDQTQREHH
     LGDQARTWLE YAAILHDVGY HINPRQHHKH AYYLIKHSDL GGLTAEDIDV IANIARYHRR
     ALPTVKHEEF TSLPPRLQRT VKILASLLRI ADGLDRTHFS LIQRLQVKLG KLVAIDVHLT
     GDAEMELWAA KSRADLFEQV FRRRVQFTGV PIEARKS
//