ID A0A0S6UP00_9BRAD Unreviewed; 341 AA.
AC A0A0S6UP00;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:GAJ33194.1};
GN ORFNames=BDOA9_0123890 {ECO:0000313|EMBL:GAJ33194.1};
OS Bradyrhizobium sp. DOA9.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=1126627 {ECO:0000313|EMBL:GAJ33194.1};
RN [1] {ECO:0000313|EMBL:GAJ33194.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DOA9 {ECO:0000313|EMBL:GAJ33194.1};
RX PubMed=25710540; DOI=10.1371/journal.pone.0117392;
RA Okazaki S., Noisangiam R., Okubo T., Kaneko T., Oshima K., Hattori M.,
RA Teamtisong K., Songwattana P., Tittabutr P., Boonkerd N., Saeki K.,
RA Sato S., Uchiumi T., Minamisawa K., Teaumroong N.;
RT "Genome Analysis of a Novel Bradyrhizobium sp. DOA9 Carrying a Symbiotic
RT Plasmid.";
RL PLoS ONE 10:e0117392-e0117392(2015).
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; DF820425; GAJ33194.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S6UP00; -.
DR STRING; 1126627.BDOA9_0123890; -.
DR eggNOG; COG1052; Bacteria.
DR Proteomes; UP000066441; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR CDD; cd05299; CtBP_dh; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR043322; CtBP.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719}.
FT DOMAIN 28..107
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 108..286
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 341 AA; 37311 MW; D386FF6F45C8E258 CRC64;
MTPKGASFTV AGSDYSYERE ALDPIDAEIV EAPADEAGFI AAAKNADAIY AKGIPITKSI
IDALESCKVI TLGSVGVDSV DVKAATARGI PVTNIPDTFI EEVADHAMML LLAGFRRLVE
QDRMVRDGRW AEGRPALLKI PRLMGQTLGF ISFGRVARAV AKRAAPFGLR MMAYDPFIQE
TLMYDHGVIP ATLNEVLSQS DFVSMHAPAR PEVHHMLTEK HFRQMKKGSI FINTGRGATV
DEESLIKALQ EGWIAHAALD VLEKEPPSHN NPLLGMEHVT LTAHVASASA RFDEARKRRV
GYELSLVLQG MWPVSCVNPS VLQNTALRRW QPVSMDRGPN S
//
