ID A0A0S6VWU4_9BACT Unreviewed; 820 AA.
AC A0A0S6VWU4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:GAK49905.1};
GN ORFNames=U14_01129 {ECO:0000313|EMBL:GAK49905.1};
OS Candidatus Moduliflexus flocculans.
OC Bacteria; Candidatus Moduliflexota; Candidatus Moduliflexia;
OC Candidatus Moduliflexales; Candidatus Moduliflexaceae.
OX NCBI_TaxID=1499966 {ECO:0000313|EMBL:GAK49905.1};
RN [1] {ECO:0000313|EMBL:GAK49905.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sekiguchi Y., Ohashi A., Parks D.H., Yamauchi T., Tyson G.W.,
RA Hugenholtz P.;
RT "First genomic representation of candidate bacterial phylum KSB3 points to
RT enhanced environmental sensing as a trigger of wastewater bulking.";
RL PeerJ 3:e740-e740(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; DF820455; GAK49905.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S6VWU4; -.
DR STRING; 1499966.U14_01129; -.
DR HOGENOM; CLU_000445_107_12_0; -.
DR Proteomes; UP000030700; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 2.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.20.120.1530; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF18947; HAMP_2; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM00304; HAMP; 3.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030700};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 304..356
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 475..525
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 530..745
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 552..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..792
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..820
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 820 AA; 90259 MW; B011A70AD46AB694 CRC64;
MRWNVFNRFF IPTLSTIIIG AGVIMFVAYT SARSALQTEI TREMEQASER LAGQIEEWLR
NLQLDVLQQS ERNITVNVLK NPNDWQGIQT ANLALKRLKE RYQYVVANIV NLDGMTLASS
TAENVGTARY DDRAYFQESL AGKVAISSVI RSRTTGEPVL ACSAPVLSEE RVIGVFLVSI
SLNSVTDKFI APIHIGEKGY AYMLEKDGTF ISHPEKERIL DQKITDFEFG QDLLAAHEGL
FTYVWKGNPK QVYLSQVPLT GWTVAVGADM NDMFSPVAHL RQTVFALTLA MIGGVSLVIW
LVAKNLTRPL VRGVAFAKAI ASGDIQAELN VRRSDEIGEL AIALGGMKSR IQEALRETER
LTRTIQAGTL HERGSAAKFQ GCWRDLIVGM NGMIDAFMDP FQVTAESLKR IARGDIPERL
THQYAGDFNE IQEHVNGLID AMNDISAIAE QIANGNLTVA AKERSEQDRL MSALNRMIAA
LTDVVGMAEE IAAGNLTVDV RERSEHDRLM IALNAMVKRL HEIVISVKAA ARNVADGSMQ
MNLSAQEVAD GASQQSAAAE QASASMEQMA SNIRQSADNA IQTEKIAMKS AADAQKSGEA
VAQTVQAMQQ IAKKITIIEE IAQETRLLSL NATIEAARAQ EHGRGFAVVA AEVRALAQRS
HDAAEEINEL TRSSLAVSSV AGEMLAQLVP DIRKTSELVM EITAATSEQS SGSAQINNAI
QQLDHVIQQN TATAEEMASM AEQLTGQARQ LQIAMNYFKV NDEHWDGDLP EQPEERPHPS
DKMMKKIVAS QREKSWGRPS QRSVSDLTEP DEYDDQFERF
//
