ID   A0A0S6W4A7_9BACT        Unreviewed;       420 AA.
AC   A0A0S6W4A7;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:GAK52993.1};
GN   ORFNames=U14_04252 {ECO:0000313|EMBL:GAK52993.1};
OS   Candidatus Moduliflexus flocculans.
OC   Bacteria; Candidatus Moduliflexota; Candidatus Moduliflexia;
OC   Candidatus Moduliflexales; Candidatus Moduliflexaceae.
OX   NCBI_TaxID=1499966 {ECO:0000313|EMBL:GAK52993.1};
RN   [1] {ECO:0000313|EMBL:GAK52993.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sekiguchi Y., Ohashi A., Parks D.H., Yamauchi T., Tyson G.W.,
RA   Hugenholtz P.;
RT   "First genomic representation of candidate bacterial phylum KSB3 points to
RT   enhanced environmental sensing as a trigger of wastewater bulking.";
RL   PeerJ 3:e740-e740(2015).
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
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DR   EMBL; DF820459; GAK52993.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S6W4A7; -.
DR   STRING; 1499966.U14_04252; -.
DR   HOGENOM; CLU_018816_1_2_0; -.
DR   Proteomes; UP000030700; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.420.20; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   NCBIfam; TIGR01730; RND_mfp; 1.
DR   PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR   PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030700}.
FT   DOMAIN          86..321
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
FT   REGION          28..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          397..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          121..193
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        28..52
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   420 AA;  45611 MW;  33C40CD78F0BF58D CRC64;
     MKKLIGIIII LALLGLLGWR IYQRIQEASA SKTPTRQPTA AGSPQGQGSR PGGGTFGKQA
     VAVEVAPVKQ QTLQEMGQYT GSLSPQSQFV VTANVSGRLE RLLVNIGDRV KQNQVIATID
     AELFQQQVER AQADLDVAKA NLTEAESTLF AAQREFERSK TLSQGNILSQ SKLDAAEAEY
     NAAEARVKVA QANVASRESA LKTAQLNLSY TSVKATWSGD KGERVIAERF ASEGALLKAN
     DQIVSVVDIR SIICVINVIE RDYFRIKPGQ QASVTTDAFP GQIFDGRVAR IAPILKETSR
     QAAIEIDIPN PNELLKPGMF ARVQLQFDEI PNATVVPVAA LVRRNEQQGV FVVDEQQMSA
     KFVPVTVGVT NAEVAQILAP PLSGIVVTLG QHLLEDGSSL TLPQQQTPDG ERRQRPEERR
//