ID A0A0S6X224_9SPHN Unreviewed; 364 AA.
AC A0A0S6X224;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 03-MAY-2023, entry version 26.
DE SubName: Full=Hemolysin {ECO:0000313|EMBL:GAM05291.1};
GN ORFNames=MBENS4_2289 {ECO:0000313|EMBL:GAM05291.1};
OS Novosphingobium sp. MBES04.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1206458 {ECO:0000313|EMBL:GAM05291.1};
RN [1] {ECO:0000313|EMBL:GAM05291.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MBES04 {ECO:0000313|EMBL:GAM05291.1};
RA Ohta Y., Nishi S., Kobayashi K., Tsubouchi T., Iida K., Tanizaki A.,
RA Kurosawa K., Adachi A., Nishihara M., Sato R., Hasegawa R., Hatada Y.;
RT "Draft Genome Sequence of Novosphingobium sp. Strain MBES04, Isolated from
RT Sunken Wood from Suruga Bay, Japan.";
RL Genome Announc. 3:e01373-14(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DF850488; GAM05291.1; -; Genomic_DNA.
DR RefSeq; WP_039390823.1; NZ_DF850488.1.
DR AlphaFoldDB; A0A0S6X224; -.
DR STRING; 1206458.MBENS4_2289; -.
DR HOGENOM; CLU_015237_4_1_5; -.
DR OrthoDB; 9797674at2; -.
DR Proteomes; UP000053513; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF4; UPF0053 PROTEIN SLL1254; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..180
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 199..259
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 265..323
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 342..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 364 AA; 40302 MW; 1BA33FA6E8BED4BA CRC64;
MALLVFYVAL ALCVSFLCSL LESSMLTLTP SQVRTFEQRG TPWARKLKRL KDDVDRPLAA
ILTLNTIAHT MGAAGAGAQY AKLYGSGSEA VFAALLTVAI LILTEIIPKT IGARYATGIA
PFCAWILPPM MVVLAPLVWF SRQITKLIAL GRTAETPRHR EELLAVTSLG QASGQIDTAE
ARFLNNLLQL DRIKTADVMT PRTVVFSLSQ DIALDELTEK VRKSPFTRIP VSGEGVDEIR
GFVIKHDVLD LLMDEDCDEQ GFADLIRPLP SVLDQLSVDR LFHRFISEHH HILMVVDEYG
SFLGLVTLED VLETIFGFEI VDELDAVDDL QEYARELSRR RAEAATRMKT PAPAAAPERR
AARD
//
