ID A0A0S6X5I6_9SPHN Unreviewed; 375 AA.
AC A0A0S6X5I6;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Aryl-alcohol dehydrogenase {ECO:0000313|EMBL:GAM06786.1};
GN ORFNames=MBENS4_3782 {ECO:0000313|EMBL:GAM06786.1};
OS Novosphingobium sp. MBES04.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1206458 {ECO:0000313|EMBL:GAM06786.1};
RN [1] {ECO:0000313|EMBL:GAM06786.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MBES04 {ECO:0000313|EMBL:GAM06786.1};
RA Ohta Y., Nishi S., Kobayashi K., Tsubouchi T., Iida K., Tanizaki A.,
RA Kurosawa K., Adachi A., Nishihara M., Sato R., Hasegawa R., Hatada Y.;
RT "Draft Genome Sequence of Novosphingobium sp. Strain MBES04, Isolated from
RT Sunken Wood from Suruga Bay, Japan.";
RL Genome Announc. 3:e01373-14(2015).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; DF850489; GAM06786.1; -; Genomic_DNA.
DR RefSeq; WP_039395501.1; NZ_DF850489.1.
DR AlphaFoldDB; A0A0S6X5I6; -.
DR STRING; 1206458.MBENS4_3782; -.
DR HOGENOM; CLU_026673_14_1_5; -.
DR OrthoDB; 9770544at2; -.
DR Proteomes; UP000053513; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08278; benzyl_alcohol_DH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43350; NAD-DEPENDENT ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43350:SF2; PKS_ER DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 12..365
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 375 AA; 38934 MW; D40011F613B23A42 CRC64;
METRAAVLER AGDEFVLQDV MVEEPRADEV VVRIEGVGLC HSDIVFAEGH RPYPMPAVLG
HEGAGIVVSI GSEVTDFAPG DAVILGFSSC EACPRCDEGL PGYCADFAPL NFIGSRRDGT
TAYRRGDTKV ASHFFGQSSF ARHAVTRAGN LVKVPETSLD LSLLGPLGCG IQTGAGAVMR
ALACAAGSSL VVVGGGSVGL SALMAGSVQG CAKIVLVEPM AERRALAMEL GASATIDPLA
GPLTEQILAL LPGGADYIVD TTGRPDVATG ALDSLAVHGT LALLGVPHDA AATIPLPLSR
TMLRGHRVIG VVEGDSDQKT FIPELIALRE AGRFPFDRLI RTFPLSQINE AIAAQARGEC
IKVVLLPDAD CAEES
//
