ID A0A0S7BAY4_9CHLR Unreviewed; 448 AA.
AC A0A0S7BAY4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=inorganic diphosphatase {ECO:0000256|ARBA:ARBA00012146};
DE EC=3.6.1.1 {ECO:0000256|ARBA:ARBA00012146};
DE AltName: Full=Pyrophosphate phospho-hydrolase {ECO:0000256|ARBA:ARBA00032535};
GN ORFNames=LARV_02476 {ECO:0000313|EMBL:GAP14702.1};
OS Longilinea arvoryzae.
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Longilinea.
OX NCBI_TaxID=360412 {ECO:0000313|EMBL:GAP14702.1};
RN [1] {ECO:0000313|EMBL:GAP14702.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KOME-1 {ECO:0000313|EMBL:GAP14702.1};
RA Sekiguchi Y., Ohashi A., Matsuura N., Tourlousse M.D.;
RT "Draft Genome Sequences of Anaerolinea thermolimosa IMO-1, Bellilinea
RT caldifistulae GOMI-1, Leptolinea tardivitalis YMTK-2, Levilinea
RT saccharolytica KIBI-1,Longilinea arvoryzae KOME-1, Previously Described as
RT Members of the Anaerolineaceae (Chloroflexi).";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=diphosphate + H2O = H(+) + 2 phosphate; Xref=Rhea:RHEA:24576,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:43474; EC=3.6.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000926};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
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DR EMBL; DF967972; GAP14702.1; -; Genomic_DNA.
DR RefSeq; WP_075073939.1; NZ_DF967972.1.
DR AlphaFoldDB; A0A0S7BAY4; -.
DR STRING; 360412.LARV_02476; -.
DR OrthoDB; 9766150at2; -.
DR Proteomes; UP000055060; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004427; F:inorganic diphosphate phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.310.20; DHHA2 domain; 1.
DR Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR001667; DDH_dom.
DR InterPro; IPR038763; DHH_sf.
DR InterPro; IPR004097; DHHA2.
DR InterPro; IPR038222; DHHA2_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF22; MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01368; DHH; 1.
DR Pfam; PF02833; DHHA2; 1.
DR SMART; SM01131; DHHA2; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF64182; DHH phosphoesterases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000055060}.
FT DOMAIN 321..446
FT /note="DHHA2"
FT /evidence="ECO:0000259|SMART:SM01131"
SQ SEQUENCE 448 AA; 48859 MW; B83D9E219CD8139A CRC64;
MQTPIYVIGH VNPDTDSIAA AASYAWLLRE RDGLDTIAAR AGATNAQTSW VLKYLGMEAP
ILLNDASPRF ESVMRRFDTT LPEKPLRDAW SVASRTGGIA PLVNLDGTPF GLVNGRSLFE
FLFHLVGPHP KQQEARISEI LEYPCNLAAD TKVAKFQAST RIRDVITRIL REEGDEFIVT
DDEGHYVGVC RQRDLLNPPR LKIVLVDHNE VSQAVGSLDE AELLEILDHH RLGNPSTRTP
IRFSVDIVGS TSTLVSERIE DAGLSAPPLL AGLMLAGLLS DTLILASPTT TERDRLAADR
LARWAFVGGS VLANETIRSY GEKVLAAGAG LGARAPSEIV SSDMKIYRSG GFQFAVAQAE
VSNLFEISEH LEALTKALEA LREQKGLDFA MLMVTDVVRG TSRLLVANQP PLLEDLPYPP
QTDGTRLAEG VVSRKKQLLP VVLGLLER
//
