ID A0A0S7BI14_9CHLR Unreviewed; 744 AA.
AC A0A0S7BI14;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=ATP-dependent RecD-like DNA helicase {ECO:0000256|HAMAP-Rule:MF_01488};
DE EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_01488};
GN Name=recD2 {ECO:0000256|HAMAP-Rule:MF_01488};
GN ORFNames=LARV_02576 {ECO:0000313|EMBL:GAP14800.1};
OS Longilinea arvoryzae.
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Longilinea.
OX NCBI_TaxID=360412 {ECO:0000313|EMBL:GAP14800.1};
RN [1] {ECO:0000313|EMBL:GAP14800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KOME-1 {ECO:0000313|EMBL:GAP14800.1};
RA Sekiguchi Y., Ohashi A., Matsuura N., Tourlousse M.D.;
RT "Draft Genome Sequences of Anaerolinea thermolimosa IMO-1, Bellilinea
RT caldifistulae GOMI-1, Leptolinea tardivitalis YMTK-2, Levilinea
RT saccharolytica KIBI-1,Longilinea arvoryzae KOME-1, Previously Described as
RT Members of the Anaerolineaceae (Chloroflexi).";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase.
CC Has no activity on blunt DNA or DNA with 3'-overhangs, requires at
CC least 10 bases of 5'-ssDNA for helicase activity. {ECO:0000256|HAMAP-
CC Rule:MF_01488}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01488};
CC -!- SIMILARITY: Belongs to the RecD family. RecD-like subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01488}.
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DR EMBL; DF967972; GAP14800.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S7BI14; -.
DR STRING; 360412.LARV_02576; -.
DR Proteomes; UP000055060; Unassembled WGS sequence.
DR GO; GO:0043139; F:5'-3' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd17933; DEXSc_RecD-like; 1.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 1.10.10.2220; -; 1.
DR Gene3D; 2.30.30.940; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01488; RecD_like; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR006345; DNA_helicase_RecD-like.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029493; RecD-like_HHH.
DR InterPro; IPR041451; RecD-like_SH13.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR NCBIfam; TIGR01448; recD_rel; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF14490; HHH_4; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF18335; SH3_13; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01488}; DNA-binding {ECO:0000256|HAMAP-Rule:MF_01488};
KW Helicase {ECO:0000256|HAMAP-Rule:MF_01488, ECO:0000313|EMBL:GAP14800.1};
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01488};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01488}; Reference proteome {ECO:0000313|Proteomes:UP000055060}.
FT DOMAIN 138..157
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 202..221
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 354..496
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT BINDING 365..369
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01488"
SQ SEQUENCE 744 AA; 81904 MW; D4A8E6B4D75A22FC CRC64;
MSSGIIPKVN NESALQPNLP YETLAGILER ITFQNDETGY TIARLRQPGQ NGEITVVGNL
LGMNVGESVN LHGLWTLHPQ YGRQFEVRYF TIEAPTTLDG IRRYLGSGLI RGVGSSTAAL
IVNAFGLESL KVLDETPERL RELPGVGKKR AAQILAGWEE QRQIKAIMFF LQSQGVSASL
AGKIYKAYGD AAIGIVRANP YQLMTDIYGI GFKTADQIAR QTGVPTNSAQ RIRAGLLYAL
DTLSNAGHCF ALREQLTAET ARLLDLEPAL CQAQIQALLD RDELVQDGDA LYLKSLYQAE
SRVAWQLARL AGTPADRLSN FASADWSAID AAMDEYSSIH LSQEQKNAVR MALMQKVSII
TGGPGTGKST ITRNIIELAL AARLSVLLAA PTGRAAKRLS ETTGLEARTI HRLLEYTPAA
GNQFSRNAQN PLDADLIIVD EMSMVDIALM RHLVDAIGEG THLVLVGDVD QLPSVGPGNV
LRDCIHSGVL PVSRLTTIYR QADDSYIIVN AHHINQGEAP EFSKKSSDFF LFAEEDPKKA
ADWVIDLVSE RIAKNFGFDA NRDIQVLTPM HRGEAGVTEL NQRLQATLNP PAARKIELKH
GARVFREGDR VMQIHNDYDR QVFNGDIGQL QKIDLVGPTL SVNFDGRLVD YDQTQLDDLL
HAYAISIHKA QGSEFPVVVI PILMQHYMML QRNLLYTAVT RARKLVVLVG SRNAIATAVN
NQRVRQRNTR LTERLTALFS SATR
//
