ID A0A0S7CWV9_9MICC Unreviewed; 659 AA.
AC A0A0S7CWV9;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=AHiyo1_19120 {ECO:0000313|EMBL:GAP58776.1};
OS Arthrobacter sp. Hiyo1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1588020 {ECO:0000313|EMBL:GAP58776.1};
RN [1] {ECO:0000313|EMBL:GAP58776.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hiyo1 {ECO:0000313|EMBL:GAP58776.1};
RX PubMed=26764021; DOI=10.1186/s12864-016-2380-4;
RA Hiraoka S., Machiyama A., Ijichi M., Inoue K., Oshima K., Hattori M.,
RA Yoshizawa S., Kogure K., Iwasaki W.;
RT "Genomic and metagenomic analysis of microbes in a soil environment
RT affected by the 2011 Great East Japan Earthquake tsunami.";
RL BMC Genomics 17:53-53(2016).
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DR EMBL; DF952469; GAP58776.1; -; Genomic_DNA.
DR RefSeq; WP_059388312.1; NZ_DF952469.1.
DR AlphaFoldDB; A0A0S7CWV9; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000063628; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 38..89
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 93..477
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 538..617
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 659 AA; 72146 MW; F82702221EED5B72 CRC64;
MADYPTESDE TLANLLHEQR RFLPEAGFTA QANATVSDYA ESDADRLAFW ARQAERLDWS
QKWTEVLDWS NPPFAKWFIG GKLNAAYNCL DRHVVAGRGD KIAYYFEGEG GDTRTITYAQ
LTDMVCQAAN TLTDLGVTAG DRVAIYMPMI PETIVAMLAC ARIGAPHTVV FGGFSSDALR
TRIHDCDARI VITSDGAYRR GRATGLKPAV DEALLDCPDV RNVLVVRRTG QEIDWTQGRD
IWWHESVELA STDHQAEAFD AEHPLYVMYT SGTTGKPKGI LHTTGGYLTA CAYTHWAVFD
LKASSDIFWT AADIGWVTGH SYIVYGPLAN GATSVLYEGT PDSPHQGRWW EIIDKYKVSI
LYCAPTAIRT FMKWGAQIPS KYSLRSLRVI GTVGEPINPA AYIWYRENIG HNRTPVVDTW
WQTETGSIMI SPLPGVTAGK PGAAMKALPG IVADVVDDAG APVANGSGGY LVLKAPWPSM
LRTIWGDDDR YVETYWSRFP GLYFTGDGSK KDEDGDIWLL GRVDDVMNVA GHRLSTTEIE
SALVSHAKVA EAAVVGAVDE TTGQAIVAFV ILRSEAGDGG PEVVQELREH VAKEIGKIAR
PRQIMVVAEL PKTRSGKIMR RLLKDVAQDR PIGDVTTLAD SSVMDLIKAG MPGGAGRPR
//
