ID A0A0S7E6C5_9EURO Unreviewed; 797 AA.
AC A0A0S7E6C5;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Chaperone ATPase hsp78 {ECO:0000313|EMBL:GIM42802.1};
GN ORFNames=ALT_002411 {ECO:0000313|EMBL:GIM42802.1}, CNMCM8060_009105
GN {ECO:0000313|EMBL:KAF4174048.1};
OS Aspergillus lentulus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=293939 {ECO:0000313|EMBL:KAF4174048.1, ECO:0000313|Proteomes:UP000713487};
RN [1] {ECO:0000313|EMBL:GIM42802.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFM 54703 {ECO:0000313|EMBL:GIM42802.1};
RA Kusuya Y., Sakai K., Kamei K., Takahashi H., Yaguchi T.;
RT "Draft Genome sequence of the pathogenic filamentous fungus Aspergillus
RT lentulus IFM 54703T.";
RL Genome Announc. 4:e01568-15(2016).
RN [2] {ECO:0000313|EMBL:KAF4174048.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CNM-CM8060 {ECO:0000313|EMBL:KAF4174048.1};
RA dos Santos R.A.C., Steenwyk J.L., Rivero-Menendez O., Mead M.E.,
RA Silva L.P., Bastos R.W., Alastruey-Izquierdo A., Goldman G.H., Rokas A.;
RT "Genomic and phenotypic heterogeneity of clinical isolates of the human
RT pathogens Aspergillus fumigatus, Aspergillus lentulus and Aspergillus
RT fumigatiaffinis.";
RL bioRxiv 0:0-0(2020).
RN [3] {ECO:0000313|EMBL:KAF4174048.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CNM-CM8060 {ECO:0000313|EMBL:KAF4174048.1};
RA Santos R.A.C., Steenwyk J.L., Rivero-Menendez O., Mead M.E., Silva L.P.,
RA Bastos R.W., Alastruey-Izquierdo A., Goldman G.H., Rokas A.;
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF4174048.1}.
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DR EMBL; BCLY01000016; GIM42802.1; -; Genomic_DNA.
DR EMBL; JAAAPS010000087; KAF4174048.1; -; Genomic_DNA.
DR STRING; 293939.A0A0S7E6C5; -.
DR VEuPathDB; FungiDB:TMP_alenIFM54703_8337; -.
DR OrthoDB; 35211at2759; -.
DR Proteomes; UP000713487; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}.
FT DOMAIN 119..263
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 518..678
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 696..787
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT COILED 332..412
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 797 AA; 88270 MW; 633DBC086039A806 CRC64;
MASRQLARAR LLRTPALSPK RVFRPPQTLR CLPQTQSLLP RASLTAALQS ISAVRHYANG
RPHPPGGTHR MNLGGEPEKS ALEQFGVDLT EKAKKGKLDP VIGRDSEIHR TIQVLSRRTK
NNPVLIGAAG TGKTAILEGL AQRIVQGDVP ESIKDKRVIA LDLGSLIAGA KFRGDFEERL
KSVLKEVEDA QGGVILFIDE LHTLLGLGKA EGSIDASNLL KPALSRGDLQ CCGATTLNEY
RLIEKDVALA RRFQPIQVGE PSVAATISIL RGIKNKYEVH HGVRITDAAL VAAATYSNRY
ITDRFLPDKA IDLVDEAASA LRLQQESKPD VIRELDRQIT TIQIELESLR KETDISSRER
REKLQEDLKA KQEESAKLTE VWEKEKAEIE SLKRTKEELE RARFELDQAQ REGNFAKAGE
LRYSTIPSLE AKLPKEGEEA AAGGTTLIHD SVTPDDIANV VSRTTGIPVN KLMAGEVEKL
IHMEDTLRQS VRGQDEALTA VANAVRMQRA GLSGQNRPLA SFMFLGPTGV GKTELCKRMA
EFLFSTETAV LRFDMSEFQE KHTISRLIGS PAGYVGYDDA GQLTEAVRRK PYAVLLFDEF
EKAHRDISAL LLQVLDEGFL TDSQGHKVDF RNTLIVLTSN LGADILVGAD PLHSFKDYGD
AELSPDIKQA VMEVVQSAYP PEFLNRIDEF IIFKRLSREA LRDIVDIRIK ELQARLDDRR
IVLQVDNEIK DWLCEKGYDP KYGARPLNRL IAKEIGNRLA DKIIRGELTS GQTAVISFNA
DKTALEVAAD GAKEEKA
//
