ID   A0A0S7WT24_9CHLR        Unreviewed;      1217 AA.
AC   A0A0S7WT24;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN   ORFNames=AMJ37_01580 {ECO:0000313|EMBL:KPJ53313.1};
OS   Dehalococcoidia bacterium DG_18.
OC   Bacteria; Chloroflexota; Dehalococcoidia.
OX   NCBI_TaxID=1703392 {ECO:0000313|EMBL:KPJ53313.1, ECO:0000313|Proteomes:UP000053383};
RN   [1] {ECO:0000313|EMBL:KPJ53313.1, ECO:0000313|Proteomes:UP000053383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DC_18 {ECO:0000313|EMBL:KPJ53313.1};
RX   PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA   Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT   "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT   among widespread estuary sediment bacteria.";
RL   Microbiome 3:14-14(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPJ53313.1}.
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DR   EMBL; LIZO01000032; KPJ53313.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S7WT24; -.
DR   PATRIC; fig|1703392.3.peg.257; -.
DR   Proteomes; UP000053383; Unassembled WGS sequence.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003033; SCP2_sterol-bd_dom.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF02036; SCP2; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF55718; SCP-like; 1.
DR   SUPFAM; SSF48452; TPR-like; 3.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          67..199
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   1217 AA;  137360 MW;  E2C647B1D387F58F CRC64;
     MIHEGALFCG SCGRDLRKLA EGIKFPPTKE DVYAEQDAKI QSYVPRYLAE KILANKGALI
     GERKQITCLF ADVVGFTPIA EALDPEQVRS IMNGCFEILI NEVHCYEGTV NQFTGDGVMA
     LFGAPIAHED HAQRAIYAAL AAQESLSEYG EELKRKMGIS LKMRMGLNTG IVIVGSIGNN
     LRMDYTALGD TINVAARLQS LAEPGGVLVS EETFNIARGY FEFKPLSELQ LKGKVEKVKA
     CKVTGIGKIK ARIEAAELRG LTKFCGRKRD LEQLLDAFES AERGEGQVVA IVGEPGIGKS
     RLVLEFRRSM EEENFYYLEG RCPAYGETKP YSSLVQILRT HFGIGEMEGT EVCREKIQGK
     LRQDGNQLTP FLPFFLNLLS IPIQDEAFSK LELQEKRERT FEALKALLVW EAQKNPLVMV
     VEDMQSIDDS SDEFIRYLIE GIVNVPMLLL CIFRPEYQPR WPEHAYYRRL SLSQLSTEAR
     LDMFYALLGE GAEELRDPVL QLTGGNPLFI EEVIHSLIDQ GAVTRREEKL VLNKTLQEIQ
     IPSSIEGLIA SRIDRLETDL KEVLQLASVI GMEFAFQVLA VVSGMITDLK RYLLRLQTLE
     FIYEKSLFPE PAYSFKHAFT QEVAYNGLLV ELRKEYHRQV AQAIERVYQE RIDEHFEDLA
     YHYSRGEEVE KGIEYLKKAG DKAYSLCSNR EASKHYEKAL DILSGMPDSI IVKKKRLEIE
     LSLETVLLAL VENLERVEDV LSDMERIATS IGDQKWIAIA QSERAYFYTI RRRDEKAIEY
     AKGVWEKTED VETLARSGLP LMLSNFFKGQ LAEGKETCDK CLDALERSGR IHETFGFPVP
     PYVTFSTVLG YINGFQGDMG LSLKYHQRAL EVAKEANNQP GIGFSTYALG WDYVMRGQYQ
     EGIPMVREGT DILEPTKVMP YVVVAYAVLA QCYHIAGDWD LSMEYFTKCV YILGTTPGFS
     KFPVGPDYSY FADLLLDLGE IEAAKETCEE GLSVAKRDKN LWSEGEMHRA FGRIYAQSEP
     PDWKKAEAHL LQSIQCLEKL GMRLRCAVSW GELGEMYQRK GDREKAEACL EKSNRMYQEM
     GIKPLKAKRP GQATIDRALA IMRGEEVKPI APVLMTLADL MQLMPMGFRA ENAKGIDAII
     QLNFTGKEEG SWYLTIRNQG CTCESGVVEN PALTLTCSSD VWLAIAQKKM SPLKAFVTGK
     LKVKGNIKLL FKMRNLF
//