ID A0A0S7X7D3_9BACT Unreviewed; 708 AA.
AC A0A0S7X7D3;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Indolepyruvate ferredoxin oxidoreductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMS15_08650 {ECO:0000313|EMBL:KPJ58330.1};
OS Planctomycetes bacterium DG_23.
OC Bacteria; Planctomycetota.
OX NCBI_TaxID=1703414 {ECO:0000313|EMBL:KPJ58330.1, ECO:0000313|Proteomes:UP000052166};
RN [1] {ECO:0000313|EMBL:KPJ58330.1, ECO:0000313|Proteomes:UP000052166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG_23 {ECO:0000313|EMBL:KPJ58330.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPJ58330.1}.
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DR EMBL; LIZR01000137; KPJ58330.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S7X7D3; -.
DR STRING; 1703414.AMS15_08650; -.
DR PATRIC; fig|1703414.3.peg.843; -.
DR Proteomes; UP000052166; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR045025; HACL1-like.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR43710; 2-HYDROXYACYL-COA LYASE; 1.
DR PANTHER; PTHR43710:SF6; INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA; 1.
DR Pfam; PF01855; POR_N; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 562..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..163
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 410..530
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 708 AA; 77263 MW; 58535F7425A25E06 CRC64;
MRRAMETEVL NGSMAIARGI LEAGISVIAG YPGTPGTYAL DRLLEMPEAK DVDIQWSANE
KAALEVAYGA SLGGVRSVAG MKGLGLNVAL DSLMVMNLAG SLGGLVIVVG DDPGAPGSSN
EQDTRLLGAF AEIPTLEPAE VTQATELVKY AFEISERLKT PVLFRGVREL ARTEAEVTLG
RISPPRKAEF IRRKDLWKSL PQYAVSAHRK VHKKLARAAK IFSNCQFNSI EGSGDLGVVA
CGFTYTRLKQ VLEILPETKL RILKLCTVFP LPQGLTEDFL ARVKRILVLE ETEPLVEREL
NILAKKEGTR KPIFGKLTGH LPGEDETSME VIFKALRELL GEKARTPSAL RKEFRPKVSE
AGFCEDCPFV PAFEGLLEVV KELKIPRPIV AGDPGCLIRL DRPPFDFLDV KMSLGSSIGI
AEGLKRAGLS QPTIAITGDS AFMHTGLSAF ASAAANGANL LLIILDNRAV VLTGLQPRIG
TGKRARGKGK KVSLLRILRA LGADFAARIN PEDKSSVKAA FTKALKMTGL RAIVLEAPCP
RFSMASFPVD INKALAGKRF HLICGAIWFA AEPFWIFLFF CIIGYYLGAK LGVPFNWRLF
LLICPFLYVP ASVVLIPHFL VYRNATKGSS ALVDMQCPEC KKAPSVQNGR ELFKRVVEET
PCPLCGEPYK FKYTRKFKLL QGVCGGFAGV LIGSFLIAYW EYLLPLYG
//
