ID A0A0S7X9K9_9BACT Unreviewed; 1008 AA.
AC A0A0S7X9K9;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN ORFNames=AMJ46_12170 {ECO:0000313|EMBL:KPJ59185.1};
OS Latescibacteria bacterium DG_63.
OC Bacteria; Candidatus Latescibacteria.
OX NCBI_TaxID=1703781 {ECO:0000313|EMBL:KPJ59185.1, ECO:0000313|Proteomes:UP000051457};
RN [1] {ECO:0000313|EMBL:KPJ59185.1, ECO:0000313|Proteomes:UP000051457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG_63 {ECO:0000313|EMBL:KPJ59185.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPJ59185.1}.
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DR EMBL; LJNC01000028; KPJ59185.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S7X9K9; -.
DR Proteomes; UP000051457; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 573..778
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 1008 AA; 108899 MW; E14369921F2D100D CRC64;
MRIAALIVTG TVSSTVTAPE HWLALSIISL TTVLVLVRFQ SVGQGVGSRA NALVGPPLGL
AVDVVMALLL VTASAFYASM RIESQTRKAC LIRERVATLT GTVASFPEQT GNGVRLVMTT
SDCDSFGLPL EDETRVFVKI RGQLPPASPG DTLIATGVLR SPHGRRNPGG FNEADYLFVK
GSSAVLTVPA FLKPTVRRVE PPRNLLALHI APVRNWVRQV VTCNVPGGER AFLLALLLGE
RGELTEETVR SFKDSGIVHL LAVSGLHTAL VGFVALVLLR GLRLSTRAST VGGAAAVWFY
CSLSGFHPST LRASVMLSCL AASRLLGRST QLLGPLSTSC VLLLLANPKY IWDPGFQLSY
AATFSIVAAA PLREAVRSRL PIRENVWRYV LSPALTTSVA QLGVLPVLAY HFGTISAVAV
PTNLLAIPLV SGALVSALCS LAVCAVFPQL ASVSFALSWL LLRLSTLLAH VTSSLPGASL
DLLKPTAAEA LGFAVCLVAL LGCIGLTRRV PSGHHGGEGK PHRGKLGRHA RRFGTIISGL
CLSWSLCAFL GLAPRSSERH ENCLRVSFLD VGQGDAAVLR LPDGRLLLID GGESTAEWDN
AERVLTPFLR DAGKKAFDAA LITHFHSDHA GGVLKLLQAR KLREILVTPA DTSTALSLLS
RQLAKERDIT LRSVSRPDTI LHETGAELIV FHPAGLASAD TSSSSLNDSS IVVVLRSGRV
QFIFTGDVGT AVMDALSQAV EPNAVTVLKA PHHGSRLSLS ESFAEKVRPR HVVFSAGRNN
RFGHPSGDVV AAYRERGARV FRTDRDGCVS FTVCGDSLSV STAQSSDKEG RLHRARAWRT
ERRLRLLMLM LRMDSKDFGL RSLLESVLKL AKHFGQCRVF HLLGRESVRL KRTVSSHVIS
DFICLLPREV EAGIVKEIYR SHELPARELK ACRDDPGRTI ESSRRRVLEA NRHKRTVVRA
PHPSLDKVRE RERLERFSNG RQSALASDCQ NWVVLPNVSA GYEAELLS
//
