ID A0A0S7XNS2_9BACT Unreviewed; 1048 AA.
AC A0A0S7XNS2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding domain-containing protein {ECO:0000259|SMART:SM00928};
GN ORFNames=AMK68_02235 {ECO:0000313|EMBL:KPJ64145.1};
OS candidate division KD3-62 bacterium DG_56.
OC Bacteria; candidate division KD3-62.
OX NCBI_TaxID=1704032 {ECO:0000313|EMBL:KPJ64145.1, ECO:0000313|Proteomes:UP000052020};
RN [1] {ECO:0000313|EMBL:KPJ64145.1, ECO:0000313|Proteomes:UP000052020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG_56 {ECO:0000313|EMBL:KPJ64145.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPJ64145.1}.
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DR EMBL; LIZY01000040; KPJ64145.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S7XNS2; -.
DR PATRIC; fig|1704032.3.peg.239; -.
DR Proteomes; UP000052020; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF10531; SLBB; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 2.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 459..504
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
SQ SEQUENCE 1048 AA; 111344 MW; D4ED4A8BE8D428FD CRC64;
MSLADLQAPA QENWQKLKHG PDPIIWSGLA TCGLAAGQAE VLDAVAAALE HNAIRAQVVP
VGCIGVCYLE PLMDIEKPGG PRICYAQMTP DKARAVIQSY LVNDDPRPDL ALGTLGDGEI
AGIPRFFDLP MLKSQVRIVL RNVGLINPED IDHYIASGGY QGFQQALSMA PEAVIDEVTE
SGLRGRGGAG FPTGQKWRFA RQASGSPKYL ICNADEGDPG AFMDRSVLEG DPHSVLEGML
IAGYAIGASE GYIYVRSEYP LAIKRMSIAL EQMRNCGLLG ENILGSGFDF DIKIKEGAGA
FVCGEETALI ASIEGKRGMP NPRPPFPATS GLWGKPTNIN NVETFANLPV ILSRGADWFA
SYGTEKSKGT KTFSLTGKVK RSGLIEVPMG MSLGDVIFSI GGGIVDDGEL KAVQSGGPSG
GCLPARLANL PIEYESLAEA GSIMGSGGLV VLDDKTCVVD MARYFLSFTQ RESCGKCVPC
RLGTKQMEAI LEDICAGRGT PEHVTLLTDL ARAVKAGSLC GLGQTAPNPV LSTLRYFQDE
YDAHIREKRC PAAACWGLFR SPCQHACPVG VDVPGYVGMI AEGRFAEAVD LVRERNPFPA
ICGRVCTHPC ESRCQRAQID DPIAICSLKR AAADFAAASG HLWQPPLAPS NGRKVAIIGG
GPAGLTAAYH LRKRGYAPTV FEAANRLGGM LRWGIPGYRL PDDVLDKEIA DIVGLGIDVR
TGHAWGRDFT LPGLREQGYE AILLAIGAHH GVDLGMPGEA LEGVVDGVRF LRHVNSDEGM
RLDGRRVVVI GGGDVAIDAA RSALRLGADK VSLVYRRTRA EMPAHASEIA AAEEEGVELQ
FLLAPQRVVG SDRATGLECL RMSLGEFDDS GRRRPEPVPG SETVIEADLI ITAIGQTSDV
PLDDRGGLAV SRRGAIEACA NSLVTGADGV FAAGDAVTGP DTVIRAIAQG ERAAIAIDRY
LRGKTLAEEA ILVGHAPPQS SGEATDEEAE EEIKECPRAI MPCLDVERRT ALFAEVAQGF
DREQAIAEAN RCLHCERSSH AEPEGGEG
//
