ID   A0A0S7ZGW6_9SPIR        Unreviewed;       280 AA.
AC   A0A0S7ZGW6;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Semialdehyde dehydrogenase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AMS17_12565 {ECO:0000313|EMBL:KPJ86404.1};
OS   Spirochaetes bacterium DG_61.
OC   Bacteria; Spirochaetota.
OX   NCBI_TaxID=1704237 {ECO:0000313|EMBL:KPJ86404.1, ECO:0000313|Proteomes:UP000050987};
RN   [1] {ECO:0000313|EMBL:KPJ86404.1, ECO:0000313|Proteomes:UP000050987}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG_61 {ECO:0000313|EMBL:KPJ86404.1};
RX   PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA   Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT   "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT   among widespread estuary sediment bacteria.";
RL   Microbiome 3:14-14(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPJ86404.1}.
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DR   EMBL; LJNB01000181; KPJ86404.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S7ZGW6; -.
DR   Proteomes; UP000050987; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 1.10.3640.10; Semialdehyde dehydrogenase-like, C-terminal; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR028939; P5C_Rdtase_cat_N.
DR   InterPro; IPR031663; PGDH_C.
DR   InterPro; IPR037161; Semialdehyde_DH-like_C.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF03807; F420_oxidored; 1.
DR   Pfam; PF16896; PGDH_C; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          7..81
FT                   /note="Pyrroline-5-carboxylate reductase catalytic N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03807"
FT   DOMAIN          125..276
FT                   /note="Phosphogluconate dehydrogenase (decarboxylating) C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16896"
SQ   SEQUENCE   280 AA;  31081 MW;  B65070C0ED90D04D CRC64;
     MEGPLFTITI LGAAGKMGMR IHNNLIKEKH TLLLCEKSPE GIELLNKKGV EVTDMKEAVP
     TSDFVIMAVP DAVLGKISHD VVPRMKENGT FIMLDPAAAY AQEIALRDEC TFVVTHPCHP
     QLFVEQETPE ARADMFGGIA AKQDIVVALL QGDEDRFQIA VEICKWMFAP VVKAHRVTVE
     QMAILEPAMA EVVGASCVTL LKEALDEAVH RGVPEEAARA FILGHINIEL AILFKSSNPF
     SDAAYRAIQY GKKKIFKDNW REVFEESSIK EVLKMMLHPE
//