ID A0A0S7ZHR4_9SPIR Unreviewed; 325 AA.
AC A0A0S7ZHR4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 28-JUN-2023, entry version 12.
DE SubName: Full=Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha {ECO:0000313|EMBL:KPJ86641.1};
GN ORFNames=AMS17_11550 {ECO:0000313|EMBL:KPJ86641.1};
OS Spirochaetes bacterium DG_61.
OC Bacteria; Spirochaetota.
OX NCBI_TaxID=1704237 {ECO:0000313|EMBL:KPJ86641.1, ECO:0000313|Proteomes:UP000050987};
RN [1] {ECO:0000313|EMBL:KPJ86641.1, ECO:0000313|Proteomes:UP000050987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG_61 {ECO:0000313|EMBL:KPJ86641.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPJ86641.1}.
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DR EMBL; LJNB01000158; KPJ86641.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S7ZHR4; -.
DR PATRIC; fig|1704237.3.peg.497; -.
DR Proteomes; UP000050987; Unassembled WGS sequence.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 13..310
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 325 AA; 35214 MW; C60F235FB1BE53C8 CRC64;
MLPAEKLIGM YEKMLTIRFF EEKAVFLFRS GVIGGAVHPS IGQEAVAVGT CENLSNDDFI
TSTHRGHGHC IAKGADINRM MAEIIGKSDG YCRGKGGSMH IADRSIGILG SNGIVGAGIP
IAVGAAFRNK YKKENDRVVV CFFGDGGANQ GTFHESLNMA AIWKLSVIFL CENNVWAIST
RSDYASSGKS IGGRACAYGI PGAVVDGNDV LGVYSAVKKA VDRCRSGEGP TLLECKTYRI
EGHFVGDPRV YCKKEEVDVW KKRCPILAFE DYLFKNDVLT EEASKSIRGR VKKKVEDAVQ
FAENSPFPSI DTLEKDVYGS TADNA
//
