ID A0A0S8B7Y2_9PROT Unreviewed; 564 AA.
AC A0A0S8B7Y2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=3-oxosteroid 1-dehydrogenase {ECO:0000313|EMBL:KPK06923.1};
GN ORFNames=AMJ64_08005 {ECO:0000313|EMBL:KPK06923.1};
OS Betaproteobacteria bacterium SG8_39.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1703390 {ECO:0000313|EMBL:KPK06923.1, ECO:0000313|Proteomes:UP000051483};
RN [1] {ECO:0000313|EMBL:KPK06923.1, ECO:0000313|Proteomes:UP000051483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG8_39 {ECO:0000313|EMBL:KPK06923.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK06923.1}.
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DR EMBL; LJTQ01000064; KPK06923.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8B7Y2; -.
DR STRING; 1703390.AMJ64_08005; -.
DR PATRIC; fig|1703390.3.peg.2455; -.
DR Proteomes; UP000051483; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 7..545
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 564 AA; 60663 MW; A86BC35ED3E8D407 CRC64;
MTQIECDVLV VGSGAGGLSA ACTAAHHGLD VIVTEKEPFF GGTTAYSAGV IWIPVNGHAV
RAGLDDSRAA ALRYLEAEIG PHLDRAKAAA FVAHGAEMLA FLEQHTEARY LLMDNWSDYH
PDRPGASQGG RSLLPEPYDG RRLGARFREL RPPLPTMMLF GGMSVSRDDI PHLLNATRSP
VSAWHVSRLL ARYAMDRMRY PRGTRITNGN ALVARLAKSL FERDVPLWIS APAVKLLVED
DAVRGAIVER SGEAIEVRCR RGVVLASGGF PRNDALRARY YPHVAAGKRH VPLAPPGNTG
DGARLAREAG GMFQAEADQP AAWTPVSLVP RPDGSVQPYP HFIDRCKPGY IVVDRRGRRF
ANEADSYHDF VPRMIEACRE DPDVETYLVT DHRAIRRYGI GVVPPAPMPL APHLRSGYLV
SAGSPEALAA ALGVDAQGFA RTLEAYNAHA ARGEDPEFGK GSNAYHRFGG DPTHGPNPNL
APIVMPPFYA VRLVPSDLGT FIGLSTDARA RVLDVNERPI AGLYAVGNDM ASVMGGTYPG
AGITLGPAMT FGYIAGRHLA GVDA
//
