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Database: UniProt
Entry: A0A0S8BAD2_9BACT
LinkDB: A0A0S8BAD2_9BACT
Original site: A0A0S8BAD2_9BACT 
ID   A0A0S8BAD2_9BACT        Unreviewed;       413 AA.
AC   A0A0S8BAD2;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   25-APR-2018, entry version 12.
DE   RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 2 {ECO:0000256|PIRNR:PIRNR000447};
DE            EC=2.3.1.179 {ECO:0000256|PIRNR:PIRNR000447};
GN   ORFNames=AMS20_01755 {ECO:0000313|EMBL:KPK08623.1};
OS   Gemmatimonas sp. SG8_28.
OC   Bacteria; Gemmatimonadetes; Gemmatimonadales; Gemmatimonadaceae;
OC   Gemmatimonas.
OX   NCBI_TaxID=1703357 {ECO:0000313|EMBL:KPK08623.1};
RN   [1] {ECO:0000313|EMBL:KPK08623.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SG8_28 {ECO:0000313|EMBL:KPK08623.1};
RX   PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA   Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT   "Genomic resolution of linkages in carbon, nitrogen, and sulfur
RT   cycling among widespread estuary sediment bacteria.";
RL   Microbiome 3:14-14(2015).
CC   -!- FUNCTION: Catalyzes the condensation reaction of fatty acid
CC       synthesis by the addition to an acyl acceptor of two carbons from
CC       malonyl-ACP. {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- CATALYTIC ACTIVITY: (Z)-hexadec-11-enoyl-[acyl-carrier-protein] +
CC       malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-
CC       carrier-protein] + CO(2) + [acyl-carrier-protein].
CC       {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC       {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- SIMILARITY: Belongs to the beta-ketoacyl-ACP synthases family.
CC       {ECO:0000256|PIRNR:PIRNR000447, ECO:0000256|RuleBase:RU003694}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KPK08623.1}.
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DR   EMBL; LJNQ01000015; KPK08623.1; -; Genomic_DNA.
DR   PATRIC; fig|1703357.3.peg.1547; -.
DR   UniPathway; UPA00094; -.
DR   GO; GO:0033817; F:beta-ketoacyl-acyl-carrier-protein synthase II activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR017568; 3-oxoacyl-ACP_synth-2.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   PIRSF; PIRSF000447; KAS_II; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR03150; fabF; 1.
DR   PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|PIRNR:PIRNR000447};
KW   Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000447};
KW   Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000447};
KW   Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000447};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000447};
KW   Transferase {ECO:0000256|PIRNR:PIRNR000447,
KW   ECO:0000256|RuleBase:RU003694}.
FT   DOMAIN        5    413       PKS_KS. {ECO:0000259|SMART:SM00825}.
FT   ACT_SITE    163    163       {ECO:0000256|PIRSR:PIRSR000447-1}.
SQ   SEQUENCE   413 AA;  43631 MW;  7F686100DF37EDBE CRC64;
     MKRRVVVTGL GLVSPLGLTT SETWSNLVDG VSGAGPIDRF DPSALDVRFA CQVKGFDPLE
     YMDRKEVKRA DRYAHYALAA ASMAIADAGY PESFPHPERT GVIIGSGIGG ISTFEDQCKL
     YLERGPGRVS PFFVPMFIPD IASGLVSIRW NARGPNYCTV SACASSAHAL GEAFRLVQTG
     EADVMVTGGA EAAITPLAIA GFANMKALST RNDDPEHASR PFDRGRDGFV MGDGAGVLVL
     ETLEHALDRG VRIYGEVIGY GMSADAHHMT QPAPGGEGAK RAMLECMRGA SIEPTSVGYI
     NAHGTATPHG DIAETKAVKD VFGEHAYQLI VGSTKSMTGH LLGAAGALEA SITLLVMEHG
     LIPPTINLAD PDPACDLDYA PTRSVARDVD VALTNSFGFG GHNVTLALRR YPD
//
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