ID A0A0S8D7Q2_9PROT Unreviewed; 290 AA.
AC A0A0S8D7Q2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:KPK32071.1};
GN ORFNames=AMJ66_07210 {ECO:0000313|EMBL:KPK32071.1};
OS Betaproteobacteria bacterium SG8_40.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1703389 {ECO:0000313|EMBL:KPK32071.1, ECO:0000313|Proteomes:UP000051602};
RN [1] {ECO:0000313|EMBL:KPK32071.1, ECO:0000313|Proteomes:UP000051602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG8_40 {ECO:0000313|EMBL:KPK32071.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK32071.1}.
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DR EMBL; LJTS01000109; KPK32071.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8D7Q2; -.
DR PATRIC; fig|1703389.3.peg.185; -.
DR Proteomes; UP000051602; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 1..152
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 155..259
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 161
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 290 AA; 30509 MW; D4DE40EB8879D924 CRC64;
MGHGMAKHLV EKGFTTSILG HRKRAPVEDL VKRGAREASD VADLVKASDI VFLCVTGSPQ
VEDLIYRKGG ILESARAGQI VVDTSTSMPF STLKIAADLE AKDVRFVDAP LARTPVEAEE
GRLNTMVGAD AATFAEVEPA LKAFCENIFH VGDVGAGHKI KLINNFAAIG QMALTAEALA
ACARLGVDPK KYFALVSTGA ANSGLFQMVA GKAVEGDFTG MKFGLANALK DVRYYNQMAM
EAGISGAMAP AVLNTLTNAV NLGFGTPGHL VASLVESQAK LNDVEFPPRS
//
