ID A0A0S8EHQ1_9CHLR Unreviewed; 514 AA.
AC A0A0S8EHQ1;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KPK47888.1};
GN ORFNames=AMJ77_01705 {ECO:0000313|EMBL:KPK47888.1};
OS Dehalococcoidia bacterium SM23_28_2.
OC Bacteria; Chloroflexota; Dehalococcoidia.
OX NCBI_TaxID=1703396 {ECO:0000313|EMBL:KPK47888.1, ECO:0000313|Proteomes:UP000054036};
RN [1] {ECO:0000313|EMBL:KPK47888.1, ECO:0000313|Proteomes:UP000054036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM23_28_2 {ECO:0000313|EMBL:KPK47888.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK47888.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LJUA01000011; KPK47888.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8EHQ1; -.
DR STRING; 1703396.AMJ77_01705; -.
DR Proteomes; UP000054036; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 15..144
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 187..427
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 514 AA; 58395 MW; 2155FC445AE5D2A7 CRC64;
MNFLFIYIDL TAQKNRKGEL VCTPGGWFQE GIASIAACLR QAGHKVGLYH MVNPVGHDAF
VKAVRRHAPD VAGFSVYSAT FPMSSRYARW AKEAGVPLVV AGGVHAMMMP EQTLADGFDI
ACIGEGERPM VELCDRLQRG EDITTVPSLH VKTGNGIAAN PTAPLLEDLD ELPHPYFDLF
DFRHLVSSQT YTGLARISRG CPYSCTYCCN RQIRALYPNP RSYMRTHSPA GAIGYLKALR
SAYPQMRYVN FMDDILHPDE AWLEEFVPMY KREIGLPFLA QHRPGLLTER TAYLLRDAGC
YELHFGLESG NQEMRRNILK RGNISDEQII ETFRLCKKYD ITTGAYNMIG LPFETMAMTL
ETIKLNAIVA PNRVFNPIFT PYPGTELHRV AAEAGLVPEQ PDYETEVIVD NPGFRPKQVL
FVRAYFKPFV DAYRLARRLP GLTRRPVEAM LDRVFLFPFL PYGLLTRAGE GWMDFQAGMK
AFVRQRFPWL YLRLRDWLTG KRIAKPTEEG QPER
//
