ID A0A0S8F6Z7_9GAMM Unreviewed; 586 AA.
AC A0A0S8F6Z7;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=AMJ59_22145 {ECO:0000313|EMBL:KPK56512.1};
OS Gammaproteobacteria bacterium SG8_31.
OC Bacteria; Pseudomonadota; Gammaproteobacteria.
OX NCBI_TaxID=1703405 {ECO:0000313|EMBL:KPK56512.1, ECO:0000313|Proteomes:UP000051321};
RN [1] {ECO:0000313|EMBL:KPK56512.1, ECO:0000313|Proteomes:UP000051321}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG8_31 {ECO:0000313|EMBL:KPK56512.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK56512.1}.
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DR EMBL; LJTI01000116; KPK56512.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8F6Z7; -.
DR PATRIC; fig|1703405.3.peg.5129; -.
DR Proteomes; UP000051321; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52964; TolB, N-terminal domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 7..121
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REPEAT 454..487
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 491..524
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 168..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 64609 MW; 75CF603E306CEB45 CRC64;
MERRLAAILT ADAVGYTQMM ARDEVATLET LDAYRSIMGG LIKQHGGRVV DAVGDNLLAE
FPSAVDAVQC AIEIQRQLAE NNAERPEDRQ MRFRIGINVG DLIVIGDRIV GDGVNVAARI
EAEATPGSVA ISRAVLDQVD GKLPLNLRDK GEFSLKNVPR PVRIYEIEHK PDDEERDPDD
SRAGIEPQVP GFGGRSAIAV LPFRNLSADP NQEYFADGLA EDLITSLAAL RVYPIISRNS
SFAYKDKPTD PRQAGKDLGA HYIVTGSVRK VGDRIRVNAE LVDSGDGRQV WSGRYDREIS
DIFEVQDEIT ASIAGAVGPA LFQSEMLHAI RRAPKNADAW DCVHRGMWHL YRYTREGVAK
ARAWAARALE LQPDSATAYC VIAFSHMYEV IYQWVDSREE PLRAAMQAAE HAVAADRDDP
MSLTALGFAC SLCGHRDRAV AVLERAVQAN PSSALAFWSL GATLTTAGRP DEGIPMVEKA
MRLSPQDPLM NEFLFTIGSA HFMAERYDEA IQFAQRSLDI KSDQPGAWRI IAAASALLGK
LDEARRALGQ MIRLAPDLTE ERLRVFLRET DVERYVRGLR LAGWSG
//
