ID A0A0S9RC77_9ACTN Unreviewed; 1156 AA.
AC A0A0S9RC77;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Nuclease {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASF37_01690 {ECO:0000313|EMBL:KQP79750.1};
OS Aeromicrobium sp. Leaf289.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=1736324 {ECO:0000313|EMBL:KQP79750.1, ECO:0000313|Proteomes:UP000051640};
RN [1] {ECO:0000313|Proteomes:UP000051640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf289 {ECO:0000313|Proteomes:UP000051640};
RA Garrido-Oter R., Mueller D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000051640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf289 {ECO:0000313|Proteomes:UP000051640};
RA Vorholt J.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQP79750.1}.
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DR EMBL; LMNK01000001; KQP79750.1; -; Genomic_DNA.
DR RefSeq; WP_056578747.1; NZ_LMNK01000001.1.
DR AlphaFoldDB; A0A0S9RC77; -.
DR OrthoDB; 3197455at2; -.
DR Proteomes; UP000051640; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17934; DEXXQc_Upf1-like; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR038720; YprB_RNase_H-like_dom.
DR NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF13482; RNase_H_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051640}.
FT DOMAIN 82..225
FT /note="PD-(D/E)XK endonuclease-like"
FT /evidence="ECO:0000259|Pfam:PF12705"
FT DOMAIN 316..507
FT /note="YprB ribonuclease H-like"
FT /evidence="ECO:0000259|Pfam:PF13482"
FT DOMAIN 952..1126
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
SQ SEQUENCE 1156 AA; 125830 MW; C78896DBBCAB54D5 CRC64;
MVMLVDDGSF VLSPSDLTAS AGCEFAWLRT VDVRRGLVTP PTSEPDLMMD RLAELGDEHE
RRYVEQLRSE GRNVVEIARP EPYDPTTLAA AMTKTLEALE SGVDVVAQAV LTDGGFGGQA
DFLVRDADGR YEVWDAKLAR HAKVTALLQI AGYADLLDQH GIPRSPIGRL ILGNGEFHDQ
DLDDVVAVYR HRRSNLEALL QRHLDSGAPA DWNAADIAQC GSCEHCAPEV EAHRDLLLVA
GMRRSQREYL RAAGVETIDQ LAATTITVHG LAERSWQKLQ SQAALQVASA SADGVVHQVF
DPTPIQQLPA ASAGDIFFDF EGDPLWADGT SHDAGLEYLF GWVEDDGTAD GAFTGLWADD
RAEEKAALIS FLGFLEDRWT QYPDLHVYHY APYEVTALKR LTARHTVGED FLDELLRAGV
FIDLYATVRQ SVRVSQPSYS IKYLEPLYMG ESLRGEVSNA TDSIVQYEHY RVLRADGNDE
KAQEVRANVE AYNAYDCTST MRLLGWLRDV GGWSPATHDQ ASRSTDDESA ARETTLGDAA
VVAEKLLAHL PDADRTAEEQ AVALLAAALG YHRREKKPSW WVYYSRLSEP VDEWMDLRST
LVAEGPVELV EDWAPVKNSV GRVLRMRGRL EPGSTIVEGA SVALLFDELP PGVELGPGAV
RAYCGKADVL SVEADLDGVV DVTLLHKHGK SVPTFSQLPM AAVEQGFVPD GPLEKVIQAL
ATSIDPSASI PLPATAALDV LARRSPRLVD GTFVGGQATS SDIDLVLDSI RRLDHSYLAV
QGPPGTGKTY LGSQVVRRLV ESRWKVGVVA QGHTTVETFL QKTIDAGLQP SCVAKENKSG
DTSDKPWTVL KDKPGHAKFA AEQDAGFLVG GTAWAFANDK AFDAAELDLL VIDEAGQFSL
ANTIVVGRAA KCLLLLGDPQ QLPQVSQGTH PEPVDGSALA WLTEGSATMP PERGFFLTKT
RRMHPVLTTA VSRLSYAGRL TSVAEVTTDR NLPGLHPGIH PIPVEHVGNG VHAVEEADAI
LASICELMRL RWQPSRSWGT RPMLPQDVIV VAPYNSQVAI IRQRLDSVQL FDTRVGTVDK
FQGQEAPVVM VSMTASSPAD APRGMDFLLN RNRLNVAVSR GQWAAYVFHS PRLADHLPTT
PAGLAELGSY LRLIAD
//
