ID A0A0T1W3G9_9MYCO Unreviewed; 774 AA.
AC A0A0T1W3G9;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=ASD37_27250 {ECO:0000313|EMBL:KQY03193.1};
OS Mycobacterium sp. Root135.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1736457 {ECO:0000313|EMBL:KQY03193.1, ECO:0000313|Proteomes:UP000051127};
RN [1] {ECO:0000313|EMBL:KQY03193.1, ECO:0000313|Proteomes:UP000051127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root135 {ECO:0000313|EMBL:KQY03193.1,
RC ECO:0000313|Proteomes:UP000051127};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQY03193.1, ECO:0000313|Proteomes:UP000051127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root135 {ECO:0000313|EMBL:KQY03193.1,
RC ECO:0000313|Proteomes:UP000051127};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQY03193.1}.
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DR EMBL; LMEZ01000009; KQY03193.1; -; Genomic_DNA.
DR RefSeq; WP_056559404.1; NZ_LMEZ01000009.1.
DR AlphaFoldDB; A0A0T1W3G9; -.
DR STRING; 1736457.ASD37_27250; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000051127; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051127};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 16..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..567
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..693
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..375
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 408..737
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 752..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 774 AA; 81117 MW; E58E8C8487A35789 CRC64;
MLHRIAQAAI AAPRRILIGA ALVMVAAAIF GIPVAKSLSA GGFQDPNAES SQAGRLLTDK
FGQGDMQMLL TVTAPDGIRS PQATRVADDV LARLKQSPHV ADVTSAWTVP PAAAKELTST
DGTSGLIVAG ITGGENDAQK YASDLSDAVT QDRDGVTVRS GGLAIVNAQI TSQTERDLLL
MESIAIPLSF LVLVWVFGGL VAAALPMIVG GLAIVGSMSV LRLITLGTDV SIFALNLSTA
LGLALAIDYT LLILSRYRDE LADGVPRDKA LIRTMSTAGR TVLFSATTVA LSMAAMLMFP
MYFLKSFAYA GVATVAFAAA AAVIVTPAAI WLLGDRLDGL DVRRPLRRLT RRDEPAPKPV
DQIFWYRSTK AVMRNAIPIG LAVVVVLLAL GAPFLSVRWG FPDDRVLPSS ASAHQVGDQL
RDDFADDSST AVTVVIPDAD GLSPSAFGRY AADLSRVSDV TSVSAPVGTF VGGARVGPPS
APTGVADGSA YLTVDGTAPL FSDASEAQLD QLHGVAGPDG RGVVLGGVAQ INRDSVEAIT
TRLPWVLGLI AVITFGLLFL LTGSVLLPIK AVLLNVLSLT AAFGALVWIF QDGHLNALGT
TPTGTLVANM PVLLFCIAFG LSMDYEVFLV ARIREYWLGL RANGDATPSG LRAIHAARAD
NDEAVALGLA RTGRVITAAA LVMSISFAAL IAAEVSFMRM FGVGLTLAVL VDATLVRMVL
VPAFMHALGG WNWWAPKPLV WLHQRIGISE SGPEPDHPIR PTTDLGMVAS ADNR
//
