ID A0A0T2YIY7_9BURK Unreviewed; 1028 AA.
AC A0A0T2YIY7;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Multidrug transporter AcrB {ECO:0000313|EMBL:KRB98883.1};
GN ORFNames=ASE11_11175 {ECO:0000313|EMBL:KRB98883.1};
OS Hydrogenophaga sp. Root209.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Hydrogenophaga.
OX NCBI_TaxID=1736490 {ECO:0000313|EMBL:KRB98883.1, ECO:0000313|Proteomes:UP000050889};
RN [1] {ECO:0000313|Proteomes:UP000050889}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root209 {ECO:0000313|Proteomes:UP000050889};
RA Garrido-Oter R., Bai Y.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRB98883.1, ECO:0000313|Proteomes:UP000050889}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root209 {ECO:0000313|EMBL:KRB98883.1,
RC ECO:0000313|Proteomes:UP000050889};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRB98883.1}.
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DR EMBL; LMIE01000030; KRB98883.1; -; Genomic_DNA.
DR RefSeq; WP_056274707.1; NZ_LMIE01000030.1.
DR AlphaFoldDB; A0A0T2YIY7; -.
DR STRING; 1736490.ASE11_11175; -.
DR OrthoDB; 9757904at2; -.
DR Proteomes; UP000050889; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF14; BLL4319 PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 848..867
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 874..894
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 900..921
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 949..971
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 977..1003
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1028 AA; 111897 MW; 69C44A4AADCCB7B6 CRC64;
MQLPEIAIRR PVFATVLSLL ILLIGFVSFA GLTVREYPRI DEPTVTVTTR FGGASSEVIE
SQVTKVLEDS LAGIEGVDII TSISRQEQSQ ITVRFKLERD PDSAAADVRD KVSRVRQRLP
DDVDEPTIAK VEADASPVIW LALNSDTITS LELSDLANRL IKPRLQTAPG AADVRVWGER
RFSMRIWIDP DRLAAYGLTV QDVEDALRRS NLEVPAGRIE SSLREFNVTA ATDVQTPEQF
RAIGIRTVSG QTIRIDDVAR VEQAPQDERT SVRYNGRDAI SLGVIRQATA NPLELSAAVQ
EMLPRIIEEL PEGVSIEVAN DNSIFIDRSI KAVYTTIAEA AVLVALVIFV FLRTLRASVI
PLITIPVSLI GSFALMALFG FSINTLTLLA LVLAIGLVVD DAIVMLENIF RHIEEGMKPF
EAAIQGAREI GFAIVAMTLT LAAVYAPLAF TPGRTGRLFA EFALALAGAV VVSGFVALTL
SPMMCSKLLR HADKPSRFDR FMERVLTGVN TAYDRALGRS LNVRWLVVAV MLSSAAGSWW
LLQTTRSELA PMEDRGVVLA NINGPDGATL AYTRRYAEAI EKMATEQSEF DRIFTIVGNP
SVAQASVVMR GKAWEERDRT TMEIARAMAP GMAALPGVSA FPITPPSLGQ GFRERPINFV
IVTSDTYENL SANVRKFQDR LAQNPGFVQV DTDLRLNKPE IRMDVDRERA ADMGVGVDTI
ARTVETMLGG RVVTRYKRDG EQYDVVVQTV SANRSTPEDI DRLFVRGRGD AMIPLGSLVT
TREVVVPREL NHFGQRRSAS ITANISPTYS LGEALGFMEQ TASEILPAGY ATDLNGQSRE
FRNSSGSLAI VFVLSLLFIY LVLAAQFESF VDPLIILLSV PLSMLGALLA LKLSGGTLNV
FSQIGLITLV GLISKHGILI VEFANQLREQ GVDKLEAVKR SAALRLRPIL MTTGAMVLGA
IPLALASGAG AESRQQIGWV IVGGMSVGTL LTIFVVPTMY SLLSRAKSHK PKHPLAGEDG
HAEVIPAK
//
