ID A0A0T5NSE5_9RHOB Unreviewed; 350 AA.
AC A0A0T5NSE5;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:KRS11834.1};
GN ORFNames=XM53_14145 {ECO:0000313|EMBL:KRS11834.1};
OS Roseovarius atlanticus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=1641875 {ECO:0000313|EMBL:KRS11834.1, ECO:0000313|Proteomes:UP000051295};
RN [1] {ECO:0000313|EMBL:KRS11834.1, ECO:0000313|Proteomes:UP000051295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R12B {ECO:0000313|EMBL:KRS11834.1,
RC ECO:0000313|Proteomes:UP000051295};
RA Li G., Lai Q., Shao Z., Yan P.;
RT "The draft genome sequence of Roseovarius sp.R12b.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRS11834.1}.
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DR EMBL; LAXJ01000016; KRS11834.1; -; Genomic_DNA.
DR RefSeq; WP_057794401.1; NZ_LAXJ01000016.1.
DR AlphaFoldDB; A0A0T5NSE5; -.
DR STRING; 1641875.XM53_14145; -.
DR PATRIC; fig|1641875.4.peg.631; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000051295; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR012824; CobW.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02475; CobW; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 253..347
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 231..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 37585 MW; E524FBB2580D40A5 CRC64;
MTDLAKLPVT VITGFLGSGK TTLVRHLMQN PGGRRLAVVV NEFGDVGVDG DILKSCAIPD
CPAENIMELA NGCICCTVAD DFIPTIEALM ALDPRPDHIL IETSGLALPK PLLKAFDWPD
IRSKITVDGV IALADAEAVA AGRFAPDVAR VDAQRLADDS IDHETPLSEV FEDQISCADI
ILLTKPDLAG PEGVARAKEV IAAEAPRPLP VVEVAEGVVD PRVILGLEAA AEDDMDARPS
HHDDHDDHEH DDFDSVVIDL PELGDPADLV SRIEDLANSQ NILRVKGYAS VAGKPMRLLV
QAVGARVRHQ YDRPWKPDEA RRGRLVVIAE HDDVNVDAIR AVLAPAEAAE
//
